New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots

In this study, molecularly imprinted Mn-doped ZnS quantum dots were used as nanosensors to determine diazepam and its metabolites. Mn-doped ZnS quantum dots (QDs) capped with L-cysteine were prepared using a sodium thiosulfate precursor and characterized by various methods. Methacrylic acid was used...

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Detalles Bibliográficos
Autores principales: Samadi-Maybodi, Abdolraouf, Abbasifar, Javad, Malekaneh, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024321/
https://www.ncbi.nlm.nih.gov/pubmed/36942073
http://dx.doi.org/10.5812/ijpr-127351
Descripción
Sumario:In this study, molecularly imprinted Mn-doped ZnS quantum dots were used as nanosensors to determine diazepam and its metabolites. Mn-doped ZnS quantum dots (QDs) capped with L-cysteine were prepared using a sodium thiosulfate precursor and characterized by various methods. Methacrylic acid was used as a precursor for the synthesis of MIP Mn-doped ZnS QDs and then used to measure diazepam in various samples. The linear dynamic range, coefficient of determination, and detection limit were found to be 0.3 - 250 µmol/L, 0.989 and 8.78 × 10(-2) µmol/L, respectively. The interference studies showed that the prepared nanosensor was selective for diazepam and its metabolites

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