New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots

In this study, molecularly imprinted Mn-doped ZnS quantum dots were used as nanosensors to determine diazepam and its metabolites. Mn-doped ZnS quantum dots (QDs) capped with L-cysteine were prepared using a sodium thiosulfate precursor and characterized by various methods. Methacrylic acid was used...

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Autores principales: Samadi-Maybodi, Abdolraouf, Abbasifar, Javad, Malekaneh, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024321/
https://www.ncbi.nlm.nih.gov/pubmed/36942073
http://dx.doi.org/10.5812/ijpr-127351
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author Samadi-Maybodi, Abdolraouf
Abbasifar, Javad
Malekaneh, Mohammad
author_facet Samadi-Maybodi, Abdolraouf
Abbasifar, Javad
Malekaneh, Mohammad
author_sort Samadi-Maybodi, Abdolraouf
collection PubMed
description In this study, molecularly imprinted Mn-doped ZnS quantum dots were used as nanosensors to determine diazepam and its metabolites. Mn-doped ZnS quantum dots (QDs) capped with L-cysteine were prepared using a sodium thiosulfate precursor and characterized by various methods. Methacrylic acid was used as a precursor for the synthesis of MIP Mn-doped ZnS QDs and then used to measure diazepam in various samples. The linear dynamic range, coefficient of determination, and detection limit were found to be 0.3 - 250 µmol/L, 0.989 and 8.78 × 10(-2) µmol/L, respectively. The interference studies showed that the prepared nanosensor was selective for diazepam and its metabolites
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spelling pubmed-100243212023-03-19 New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots Samadi-Maybodi, Abdolraouf Abbasifar, Javad Malekaneh, Mohammad Iran J Pharm Res Research Article In this study, molecularly imprinted Mn-doped ZnS quantum dots were used as nanosensors to determine diazepam and its metabolites. Mn-doped ZnS quantum dots (QDs) capped with L-cysteine were prepared using a sodium thiosulfate precursor and characterized by various methods. Methacrylic acid was used as a precursor for the synthesis of MIP Mn-doped ZnS QDs and then used to measure diazepam in various samples. The linear dynamic range, coefficient of determination, and detection limit were found to be 0.3 - 250 µmol/L, 0.989 and 8.78 × 10(-2) µmol/L, respectively. The interference studies showed that the prepared nanosensor was selective for diazepam and its metabolites Brieflands 2022-09-05 /pmc/articles/PMC10024321/ /pubmed/36942073 http://dx.doi.org/10.5812/ijpr-127351 Text en Copyright © 2022, Author(s) https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
spellingShingle Research Article
Samadi-Maybodi, Abdolraouf
Abbasifar, Javad
Malekaneh, Mohammad
New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots
title New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots
title_full New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots
title_fullStr New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots
title_full_unstemmed New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots
title_short New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots
title_sort new fluorescent nanosensor for determination of diazepam using molecularly imprinted mn-doped zns quantum dots
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024321/
https://www.ncbi.nlm.nih.gov/pubmed/36942073
http://dx.doi.org/10.5812/ijpr-127351
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