Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them

In recent decades, a growing interest has been observed among pharmaceutical companies in producing and selling 80 FDA-approved therapeutic peptides. However, there are many drawbacks to peptide synthesis at the academic and industrial scales, involving the use of large amounts of highly hazardous c...

Descripción completa

Detalles Bibliográficos
Autores principales: Haji Abbasi Somehsaraie, Mahan, Fathi Vavsari, Vaezeh, Kamangar, Mohammad, Balalaie, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024322/
https://www.ncbi.nlm.nih.gov/pubmed/36942077
http://dx.doi.org/10.5812/ijpr-123879
_version_ 1784909077786132480
author Haji Abbasi Somehsaraie, Mahan
Fathi Vavsari, Vaezeh
Kamangar, Mohammad
Balalaie, Saeed
author_facet Haji Abbasi Somehsaraie, Mahan
Fathi Vavsari, Vaezeh
Kamangar, Mohammad
Balalaie, Saeed
author_sort Haji Abbasi Somehsaraie, Mahan
collection PubMed
description In recent decades, a growing interest has been observed among pharmaceutical companies in producing and selling 80 FDA-approved therapeutic peptides. However, there are many drawbacks to peptide synthesis at the academic and industrial scales, involving the use of large amounts of highly hazardous coupling reagents and solvents. This review focuses on hideous and observant wastes produced before, during, and after peptide synthesis and proposes some solutions to reduce them.
format Online
Article
Text
id pubmed-10024322
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Brieflands
record_format MEDLINE/PubMed
spelling pubmed-100243222023-03-19 Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them Haji Abbasi Somehsaraie, Mahan Fathi Vavsari, Vaezeh Kamangar, Mohammad Balalaie, Saeed Iran J Pharm Res Review Article In recent decades, a growing interest has been observed among pharmaceutical companies in producing and selling 80 FDA-approved therapeutic peptides. However, there are many drawbacks to peptide synthesis at the academic and industrial scales, involving the use of large amounts of highly hazardous coupling reagents and solvents. This review focuses on hideous and observant wastes produced before, during, and after peptide synthesis and proposes some solutions to reduce them. Brieflands 2022-07-30 /pmc/articles/PMC10024322/ /pubmed/36942077 http://dx.doi.org/10.5812/ijpr-123879 Text en Copyright © 2022, Author(s) https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
spellingShingle Review Article
Haji Abbasi Somehsaraie, Mahan
Fathi Vavsari, Vaezeh
Kamangar, Mohammad
Balalaie, Saeed
Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them
title Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them
title_full Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them
title_fullStr Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them
title_full_unstemmed Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them
title_short Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them
title_sort chemical wastes in the peptide synthesis process and ways to reduce them
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024322/
https://www.ncbi.nlm.nih.gov/pubmed/36942077
http://dx.doi.org/10.5812/ijpr-123879
work_keys_str_mv AT hajiabbasisomehsaraiemahan chemicalwastesinthepeptidesynthesisprocessandwaystoreducethem
AT fathivavsarivaezeh chemicalwastesinthepeptidesynthesisprocessandwaystoreducethem
AT kamangarmohammad chemicalwastesinthepeptidesynthesisprocessandwaystoreducethem
AT balalaiesaeed chemicalwastesinthepeptidesynthesisprocessandwaystoreducethem

Ejemplares similares