Cargando…

Polysaccharide Peptide Induced Colorectal Cancer Cells Apoptosis by Down-Regulating EGFR and PD-L1 Expression

BACKGROUND: Colorectal cancer (CRC) is the most frequent death-causing disease in the world. The Trametes versicolor mushroom, a traditional Chinese medicine, has been used as anti-cancer medicine with long history. Its cultured mycelia extracts, namely polysaccharide peptide (PSP) as the major acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jian, Lin, Zhicheng, He, shubai, Liu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Brieflands 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024323/ https://www.ncbi.nlm.nih.gov/pubmed/36942063 http://dx.doi.org/10.5812/ijpr-123909

Ejemplares similares

Polysaccharide-Peptide from Trametes versicolor: The Potential Medicine for Colorectal Cancer Treatment
por: He, Zhicheng, et al.
Publicado: (2022)

Krill oil extract inhibits the migration of human colorectal cancer cells and down-regulates EGFR signalling and PD-L1 expression
por: Jayathilake, Abilasha G., et al.
Publicado: (2020)

CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell
por: He, YingYing, et al.
Publicado: (2021)

Identification of BGN and THBS2 as metastasis‐specific biomarkers and poor survival key regulators in human colon cancer by integrated analysis
por: He, Zhicheng, et al.
Publicado: (2022)

PD-L1 expression as a predictor of postoperative recurrence and the association between the PD-L1 expression and EGFR mutations in NSCLC
por: Kojima, Kensuke, et al.
Publicado: (2021)

Polymer chimera of stapled oncolytic peptide coupled with anti-PD-L1 peptide boosts immunotherapy of colorectal cancer
por: Lu, Lu, et al.
Publicado: (2022)

Milk Exosomes Transfer Oligosaccharides into Macrophages to Modulate Immunity and Attenuate Adherent-Invasive E. coli (AIEC) Infection
por: He, Yingying, et al.
Publicado: (2021)

EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%
por: Zarogoulidis, Paul, et al.
Publicado: (2017)

Influence of location-dependent sex difference on PD-L1, MMR/MSI, and EGFR in colorectal carcinogenesis
por: Choi, Jina, et al.
Publicado: (2023)

Efficacy of anti-PD-1 antibodies in NSCLC patients with an EGFR mutation and high PD-L1 expression
por: Masuda, Ken, et al.
Publicado: (2020)

Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer
por: He, YingYing, et al.
Publicado: (2021)

PD-L1 expression and its effect on clinical outcomes of EGFR-mutant NSCLC patients treated with EGFR-TKIs
por: Bai, Yuchen, et al.
Publicado: (2018)

Influence of PD‐L1 expression on the efficacy of EGFR‐TKIs in EGFR ‐mutant non‐small cell lung cancer
por: Lei, Si‐Yu, et al.
Publicado: (2023)

PD-L1 expression associated with better response to EGFR tyrosine kinase inhibitors
por: Rosell, Rafael, et al.
Publicado: (2015)

PD-L1: expression regulation
por: Zhou, Yu-Jie, et al.
Publicado: (2023)

Triple blockade of EGFR, MEK and PD-L1 has antitumor activity in colorectal cancer models with constitutive activation of MAPK signaling and PD-L1 overexpression
por: Napolitano, S., et al.
Publicado: (2019)

The association between PD-L1 and EGFR status and the prognostic value of PD-L1 in advanced non-small cell lung cancer patients treated with EGFR-TKIs
por: Tang, Yanna, et al.
Publicado: (2015)

Inhibition of yes‐associated protein down‐regulates PD‐L1 (CD274) expression in human malignant pleural mesothelioma
por: Hsu, Ping‐Chih, et al.
Publicado: (2018)

Evaluation on the Distribution of EGFR, KRAS and BRAF Genes and the Expression of PD-L1 in Different Types of Lung Cancer
por: Zhao, Rui, et al.
Publicado: (2021)

Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53
por: Zhang, Xiaoyun, et al.
Publicado: (2019)

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation
por: Monypenny, James, et al.
Publicado: (2018)

Clinicopathological analysis of PD-L2 expression in colorectal cancer
por: Guo, Peng-Da, et al.
Publicado: (2018)

Heterogeneous components of lung adenocarcinomas confer distinct EGFR mutation and PD-L1 expression
por: Cai, Yiran, et al.
Publicado: (2020)

Genetic dissection of intratumor heterogeneity of PD‐L1 expression in EGFR ‐mutated lung adenocarcinoma
por: Kunimasa, Kei, et al.
Publicado: (2023)

AKT-STAT3 Pathway as a Downstream Target of EGFR Signaling to Regulate PD-L1 Expression on NSCLC cells
por: Abdelhamed, Sherif, et al.
Publicado: (2016)

Role of regulation of PD-1 and PD-L1 expression in sepsis
por: Zhang, Teng, et al.
Publicado: (2023)

High expression of antimicrobial peptides cathelicidin-BF in Pichia pastoris and verification of its activity
por: Dong, Xufeng, et al.
Publicado: (2023)

RALT doubles down on EGFR
por: Leslie, Mitch
Publicado: (2010)

The Roles of microRNAs in Regulating the Expression of PD-1/PD-L1 Immune Checkpoint
por: Wang, Qingshui, et al.
Publicado: (2017)

RUNX1-Regulated Signaling Pathways in Ovarian Cancer
por: Chen, Yuanzhi, et al.
Publicado: (2023)

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
por: Garcia-Diaz, Angel, et al.
Publicado: (2017)

PD-L1 and PD-L2 Expression in Cervical Cancer: Regulation and Biomarker Potential
por: Rotman, Jossie, et al.
Publicado: (2020)

Chemotherapeutic Treatments Increase PD-L1 Expression in Esophageal Squamous Cell Carcinoma through EGFR/ERK Activation
por: Ng, Hoi Yan, et al.
Publicado: (2018)

Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy
por: Chen, Cheng, et al.
Publicado: (2021)

Bisecting N-Acetylglucosamine on EGFR Inhibits Malignant Phenotype of Breast Cancer via Down-Regulation of EGFR/Erk Signaling
por: Cheng, Lanming, et al.
Publicado: (2020)

miRNA Clusters with Down-Regulated Expression in Human Colorectal Cancer and Their Regulation
por: Pidíkova, Paulína, et al.
Publicado: (2020)

Transcriptional down-regulation of the retinoblastoma protein is associated with differentiation and apoptosis in human colorectal epithelial cells
por: Guy, M, et al.
Publicado: (2001)

The EGFR‐P38 MAPK axis up‐regulates PD‐L1 through miR‐675‐5p and down‐regulates HLA‐ABC via hexokinase‐2 in hepatocellular carcinoma cells
por: Liu, Zongcai, et al.
Publicado: (2021)

Down Regulation of c-FLIP(L) Enhance PD-1 Blockade Efficacy in B16 Melanoma
por: Wang, Yao, et al.
Publicado: (2019)

The Co-Expression of Programmed Death-Ligand 1 (PD-L1) in Untreated EGFR-Mutated Metastatic Lung Adenocarcinoma
por: Hsu, Ping-Chih, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4o5phap6qlqpev7gesb0gvdrhs