Cargando…

SETD8 inhibits ferroptosis in pancreatic cancer by inhibiting the expression of RRAD

BACKGROUND: As an oncogene, SETD8 can promote tumour growth and tumour cell proliferation. This study aims to reveal the relationship between SETD8 and ferroptosis in pancreatic cancer and its role in pancreatic cancer to provide a possible new direction for the comprehensive treatment of pancreatic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Zekun, Hu, Qiangsheng, Qin, Yi, Yang, Hao, Xiao, Bingkai, Chen, Weibo, Ji, Shunrong, Zu, Guangchen, Wang, Zhiliang, Fan, Guixiong, Xu, Xiaowu, Chen, Xuemin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024404/ https://www.ncbi.nlm.nih.gov/pubmed/36934248 http://dx.doi.org/10.1186/s12935-023-02899-6

Ejemplares similares

A positive feedback loop of ARF6 activates ERK1/2 signaling pathway via DUSP6 silencing to promote pancreatic cancer progression : ARF6 regulates ERK1/2 pathway by inhibiting DUSP6
por: Xiao, Bingkai, et al.
Publicado: (2022)

MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors: MEN1 promotes ferroptosis in pancreatic neuroendocrine tumors
por: Ye, Zeng, et al.
Publicado: (2022)

The potential of ferroptosis combined with radiotherapy in cancer treatment
por: Lu, Zekun, et al.
Publicado: (2023)

FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells
por: Ye, Zeng, et al.
Publicado: (2020)

Ferroptosis: Final destination for cancer?
por: Ye, Zeng, et al.
Publicado: (2020)

PITX2 in pancreatic stellate cells promotes EMT in pancreatic cancer cells via the Wnt/β-catenin pathway: PITX2 promotes pancreatic cancer progression via Wnt/β-catenin pathway
por: Wu, Di, et al.
Publicado: (2023)

Clinical outcomes of minimally invasive duodenum-preserving pancreatic head resection
por: Zu, Guangchen, et al.
Publicado: (2023)

RRAD inhibits the Warburg effect through negative regulation of the NF-κB signaling
por: Liu, Juan, et al.
Publicado: (2015)

ALDOA inhibits cell cycle arrest induced by DNA damage via the ATM-PLK1 pathway in pancreatic cancer cells
por: Chen, Haidi, et al.
Publicado: (2021)

Improved tumor control with antiangiogenic therapy after treatment with gemcitabine and nab‐paclitaxel in pancreatic cancer
por: Zhang, Zheng, et al.
Publicado: (2021)

Inhibition of histone methyltransferase SETD8 represses DNA virus replication
por: Chen, Lin, et al.
Publicado: (2022)

Pin1 promotes pancreatic cancer progression and metastasis by activation of NF‐κB‐IL‐18 feedback loop
por: Sun, Qiqing, et al.
Publicado: (2020)

RRAD expression in gastric and colorectal cancer with peritoneal carcinomatosis
por: Kim, Hee Kyung, et al.
Publicado: (2019)

Friend or Foe: Regulation, Downstream Effectors of RRAD in Cancer
por: Sun, Zhangyue, et al.
Publicado: (2023)

Value of lymphadenectomy in patients with surgically resected pancreatic neuroendocrine tumors
por: Zhang, Zheng, et al.
Publicado: (2022)

PB1975: THE RESEARCH ON THE MECHANISM OF RRAD GENE IN MULTIPLE MYELOMA
por: Yi, C., et al.
Publicado: (2022)

Function and regulation of F-box/WD repeat-containing protein 7
por: Zhang, Zheng, et al.
Publicado: (2020)

RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma
por: Yan, Yingcai, et al.
Publicado: (2019)

ABO Blood Group and the Risk of Pancreatic Neoplasms in Chinese Han Population: A Study at Shanghai Pancreatic Cancer Institute
por: Liu, Mengqi, et al.
Publicado: (2019)

Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma
por: Sun, Qiqing, et al.
Publicado: (2019)

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC
por: Xue, Wei, et al.
Publicado: (2023)

Peptide inhibition of the SETD6 methyltransferase catalytic activity
por: Feldman, Michal, et al.
Publicado: (2017)

Pevonedistat Suppresses Pancreatic Cancer Growth via Inactivation of the Neddylation Pathway
por: Xu, Junfeng, et al.
Publicado: (2022)

Targeted inhibition of the methyltransferase SETD8 synergizes with the Wee1 inhibitor adavosertib in restraining glioblastoma growth
por: Della Monica, Rosa, et al.
Publicado: (2023)

High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression
por: Qi, Jie, et al.
Publicado: (2020)

Comparison of laparoscopic and open pancreaticoduodenectomy for the treatment of distal cholangiocarcinoma: A propensity score matching analysis
por: Zhu, Yuwen, et al.
Publicado: (2022)

The dynamic conformational landscape of the protein methyltransferase SETD8
por: Chen, Shi, et al.
Publicado: (2019)

PRMT5 enhances tumorigenicity and glycolysis in pancreatic cancer via the FBW7/cMyc axis
por: Qin, Yi, et al.
Publicado: (2019)

Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD
por: Zhang, Cen, et al.
Publicado: (2014)

The pseudogene DUXAP10 promotes an aggressive phenotype through binding with LSD1 and repressing LATS2 and RRAD in non small cell lung cancer
por: Wei, Chen-Chen, et al.
Publicado: (2016)

SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition
por: Terzo, Esteban A., et al.
Publicado: (2019)

Small-Molecule Inhibitors of SETD8 with Cellular Activity
por: Blum, Gil, et al.
Publicado: (2014)

High-SETD8 inactivates p53 in neuroblastoma
por: Veschi, Veronica, et al.
Publicado: (2017)

Roles for the methyltransferase SETD8 in DNA damage repair
por: Xu, Libo, et al.
Publicado: (2022)

Solasonine Inhibits Pancreatic Cancer Progression With Involvement of Ferroptosis Induction
por: Liang, Xiaoqiang, et al.
Publicado: (2022)

Prognostic Significance of Altered ATRX/DAXX Gene in Pancreatic Neuroendocrine Tumors: A Meta-Analysis
por: Wang, Fei, et al.
Publicado: (2021)

Recruitment methods and yield rates for a multisite clinical trial exploring risk reduction for Alzheimer's disease (rrAD)
por: Szabo‐Reed, Amanda N., et al.
Publicado: (2023)

MiR-216b inhibits pancreatic cancer cell progression and promotes apoptosis by down-regulating KRAS
por: Wu, Xinquan, et al.
Publicado: (2017)

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition
por: Terzo, Esteban A., et al.
Publicado: (2019)

Methyltransferase SETD2 inhibits tumor growth and metastasis via STAT1–IL‐8 signaling‐mediated epithelial–mesenchymal transition in lung adenocarcinoma
por: Yang, Xin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f23g3dgb01aqem9tu61ghmtnnr