Above-Knee Amputation After Total Knee Replacement Infection: The Unfortunate End of an Odyssey

Total knee replacement is the gold standard for the surgical treatment of late-stage symptomatic knee osteoarthritis when conservative measures have not alleviated the problem. However, as with any surgery, there are potential dangers and complications. Of these, infection is one of the most severe and may lead to life-changing outcomes for the patient. In this case report, a patient with a history of infected primary total knee arthroplasty and numerous attempts to eradicate the patient’s infection is presented. After two unsuccessful two-stage revisions, and although arthrodesis was discussed and suggested, an above-knee amputation was finally applied to our patient.