Cargando…

Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area

OBJECTIVE: This study aimed to assess the predictive value of preoperative diffusion tensor imaging (DTI) data for surgical outcomes of patients with supratentorial glioma in the motor function area. PATIENTS AND METHODS: This is a retrospective study of 43 patients receiving navigation-guided surge...

Descripción completa

Detalles Bibliográficos
Autores principales: Duy Hung, Nguyen, Duy Linh, Nguyen, Ha Vi, Nguyen, Van Anh, Nguyen Thi, Dinh Hieu, Nguyen, Dai Ha, Duong, Minh Duc, Nguyen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024488/
https://www.ncbi.nlm.nih.gov/pubmed/36941979
http://dx.doi.org/10.2147/TCRM.S402622
_version_ 1784909115310473216
author Duy Hung, Nguyen
Duy Linh, Nguyen
Ha Vi, Nguyen
Van Anh, Nguyen Thi
Dinh Hieu, Nguyen
Dai Ha, Duong
Minh Duc, Nguyen
author_facet Duy Hung, Nguyen
Duy Linh, Nguyen
Ha Vi, Nguyen
Van Anh, Nguyen Thi
Dinh Hieu, Nguyen
Dai Ha, Duong
Minh Duc, Nguyen
author_sort Duy Hung, Nguyen
collection PubMed
description OBJECTIVE: This study aimed to assess the predictive value of preoperative diffusion tensor imaging (DTI) data for surgical outcomes of patients with supratentorial glioma in the motor function area. PATIENTS AND METHODS: This is a retrospective study of 43 patients receiving navigation-guided surgery for histopathologically demonstrated supratentorial glioma in the motor function area. All patients underwent preoperative 3 Tesla magnetic resonance imaging examinations with conventional and DTI sequences. Data on preoperative imaging and pre- and postoperative clinical characteristics of patients were retrospectively collected. Univariate and multivariate linear regressions were applied to analyze the relationships between preoperative parameters and pre- and postoperative muscle strength and the Karnofsky Performance Status (KPS) score. RESULTS: Fourteen patients had low-grade gliomas and 29 had high-grade gliomas. Although the corticospinal tract (CST) score did not differ significantly between tumor grades, edema and deviation were common in low-grade gliomas (64.3%), while destroyed and infiltrated lesions were common in high-grade gliomas (58.6%). Muscle strength improved after surgery in the deviated tract group (40%) more than in the infiltrated tract group (33.3%). Two independent indices, preoperative muscle strength (p = 0.000) and glioma-to-CST distance (p = 0.001), were linearly related to postoperative muscle strength. The preoperative KPS score was the only indicator that affected the postoperative KPS score (p = 0.000). CONCLUSION: DTI should be considered in surgical management of supratentorial gliomas in the motor function area to determine the appropriate surgical strategy and predict the nature of the tumor and postoperative motor function.
format Online
Article
Text
id pubmed-10024488
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-100244882023-03-19 Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area Duy Hung, Nguyen Duy Linh, Nguyen Ha Vi, Nguyen Van Anh, Nguyen Thi Dinh Hieu, Nguyen Dai Ha, Duong Minh Duc, Nguyen Ther Clin Risk Manag Original Research OBJECTIVE: This study aimed to assess the predictive value of preoperative diffusion tensor imaging (DTI) data for surgical outcomes of patients with supratentorial glioma in the motor function area. PATIENTS AND METHODS: This is a retrospective study of 43 patients receiving navigation-guided surgery for histopathologically demonstrated supratentorial glioma in the motor function area. All patients underwent preoperative 3 Tesla magnetic resonance imaging examinations with conventional and DTI sequences. Data on preoperative imaging and pre- and postoperative clinical characteristics of patients were retrospectively collected. Univariate and multivariate linear regressions were applied to analyze the relationships between preoperative parameters and pre- and postoperative muscle strength and the Karnofsky Performance Status (KPS) score. RESULTS: Fourteen patients had low-grade gliomas and 29 had high-grade gliomas. Although the corticospinal tract (CST) score did not differ significantly between tumor grades, edema and deviation were common in low-grade gliomas (64.3%), while destroyed and infiltrated lesions were common in high-grade gliomas (58.6%). Muscle strength improved after surgery in the deviated tract group (40%) more than in the infiltrated tract group (33.3%). Two independent indices, preoperative muscle strength (p = 0.000) and glioma-to-CST distance (p = 0.001), were linearly related to postoperative muscle strength. The preoperative KPS score was the only indicator that affected the postoperative KPS score (p = 0.000). CONCLUSION: DTI should be considered in surgical management of supratentorial gliomas in the motor function area to determine the appropriate surgical strategy and predict the nature of the tumor and postoperative motor function. Dove 2023-03-14 /pmc/articles/PMC10024488/ /pubmed/36941979 http://dx.doi.org/10.2147/TCRM.S402622 Text en © 2023 Duy Hung et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Duy Hung, Nguyen
Duy Linh, Nguyen
Ha Vi, Nguyen
Van Anh, Nguyen Thi
Dinh Hieu, Nguyen
Dai Ha, Duong
Minh Duc, Nguyen
Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area
title Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area
title_full Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area
title_fullStr Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area
title_full_unstemmed Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area
title_short Predictive Value of Preoperative Diffusion Tensor Imaging for Evaluating Postoperative Outcomes of Supratentorial Glioma in the Motor Function Area
title_sort predictive value of preoperative diffusion tensor imaging for evaluating postoperative outcomes of supratentorial glioma in the motor function area
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024488/
https://www.ncbi.nlm.nih.gov/pubmed/36941979
http://dx.doi.org/10.2147/TCRM.S402622
work_keys_str_mv AT duyhungnguyen predictivevalueofpreoperativediffusiontensorimagingforevaluatingpostoperativeoutcomesofsupratentorialgliomainthemotorfunctionarea
AT duylinhnguyen predictivevalueofpreoperativediffusiontensorimagingforevaluatingpostoperativeoutcomesofsupratentorialgliomainthemotorfunctionarea
AT havinguyen predictivevalueofpreoperativediffusiontensorimagingforevaluatingpostoperativeoutcomesofsupratentorialgliomainthemotorfunctionarea
AT vananhnguyenthi predictivevalueofpreoperativediffusiontensorimagingforevaluatingpostoperativeoutcomesofsupratentorialgliomainthemotorfunctionarea
AT dinhhieunguyen predictivevalueofpreoperativediffusiontensorimagingforevaluatingpostoperativeoutcomesofsupratentorialgliomainthemotorfunctionarea
AT daihaduong predictivevalueofpreoperativediffusiontensorimagingforevaluatingpostoperativeoutcomesofsupratentorialgliomainthemotorfunctionarea
AT minhducnguyen predictivevalueofpreoperativediffusiontensorimagingforevaluatingpostoperativeoutcomesofsupratentorialgliomainthemotorfunctionarea