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miR-16-5p Regulates Ferroptosis by Targeting SLC7A11 in Adriamycin-Induced Ferroptosis in Cardiomyocytes

INTRODUCTION: Adriamycin (ADR) is commonly used in tumor chemotherapy, but its nonreversible cardiotoxicity severely hampers its clinical application. Ferroptosis is an implicated cause of ADR-induced injury. However, the underlying molecular mechanisms remain poorly understood. This study explored...

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Detalles Bibliográficos
Autores principales: Chen, Yongquan, Deng, Yecheng, Chen, Linghua, Huang, Ziyao, Yan, Yi, Huang, Zhaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024494/
https://www.ncbi.nlm.nih.gov/pubmed/36941983
http://dx.doi.org/10.2147/JIR.S393646