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Analysis of Systemic Epigenetic Alterations in Inflammatory Bowel Disease: Defining Geographical, Genetic and Immune-Inflammatory influences on the Circulating Methylome
BACKGROUND: Epigenetic alterations may provide valuable insights into gene–environment interactions in the pathogenesis of inflammatory bowel disease [IBD]. METHODS: Genome-wide methylation was measured from peripheral blood using the Illumina 450k platform in a case-control study in an inception co...
Autores principales: | Kalla, Rahul, Adams, Alex T, Nowak, Jan K, Bergemalm, Daniel, Vatn, Simen, Ventham, Nicholas T, Kennedy, Nicholas A, Ricanek, Petr, Lindstrom, Jonas, Söderholm, Johan, Pierik, Marie, D’Amato, Mauro, Gomollón, Fernando, Olbjørn, Christine, Richmond, Rebecca, Relton, Caroline, Jahnsen, Jørgen, Vatn, Morten H, Halfvarson, Jonas, Satsangi, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024547/ https://www.ncbi.nlm.nih.gov/pubmed/36029471 http://dx.doi.org/10.1093/ecco-jcc/jjac127 |
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