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The Effect of Long-Term Inorganic Iodine on Intrathyroidal Iodothyronine Content and Gene Expression in Mice with Graves' Hyperthyroidism

BACKGROUND: The main molecular mechanism underlying acute suppression of iodine organification in normal thyroids after an excessive iodine load, that is, the Wolff–Chaikoff effect, is assumed to be suppression of iodine oxidation and iodothyronine synthesis. However, the mechanism underlying chroni...

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Detalles Bibliográficos
Autores principales:	Uchida, Toyoyoshi, Shimamura, Mika, Taka, Hikari, Kaga, Naoko, Miura, Yoshiki, Nishida, Yuya, Nagayama, Yuji, Watada, Hirotaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2023
Materias:	Immunology, Autoimmunity, and Graves' Ophthalmopathy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024588/ https://www.ncbi.nlm.nih.gov/pubmed/36565031 http://dx.doi.org/10.1089/thy.2022.0496

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