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Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis

Carotid endarterectomy (CEA) is a surgical procedure that treats the narrowed carotid arteries, which may be narrowed by atherosclerosis. Stenting is the insertion of a wire mesh scaffold into the narrowed portion of the carotid artery to keep it open by preventing blood from clotting. Using the stu...

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Autores principales: Vasavada, Advait M, Singh, Priyansha, Firdaus, Arshia, Meenashi Sundaram, Dakshin, Patel, Malvik, Singh, Ganeev, Palanisamy, Logesh, Ansari, Sana Afreen, Thummala, Sumaina, Pandya, Harsh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024598/
https://www.ncbi.nlm.nih.gov/pubmed/36942176
http://dx.doi.org/10.7759/cureus.35070
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author Vasavada, Advait M
Singh, Priyansha
Firdaus, Arshia
Meenashi Sundaram, Dakshin
Patel, Malvik
Singh, Ganeev
Palanisamy, Logesh
Ansari, Sana Afreen
Thummala, Sumaina
Pandya, Harsh
author_facet Vasavada, Advait M
Singh, Priyansha
Firdaus, Arshia
Meenashi Sundaram, Dakshin
Patel, Malvik
Singh, Ganeev
Palanisamy, Logesh
Ansari, Sana Afreen
Thummala, Sumaina
Pandya, Harsh
author_sort Vasavada, Advait M
collection PubMed
description Carotid endarterectomy (CEA) is a surgical procedure that treats the narrowed carotid arteries, which may be narrowed by atherosclerosis. Stenting is the insertion of a wire mesh scaffold into the narrowed portion of the carotid artery to keep it open by preventing blood from clotting. Using the study done over 10 years back as a point of reference, this study will seek an update on an assessment comparing CEA and stenting in studies carried out between 2015 and to date. The PICOS (population, intervention, control, outcome, and study designs) criteria were used to construct a set of inclusion and exclusion guidelines. This meta-analysis and systematic review used two forms of investigative analysis; both quantitative and qualitative assessments. From the studies, stroke (95% CI: 0.51-0.71, P < 0.001), myocardial infarction (95% CI: 1.49-3.42, P = 0.001), and stroke or death analysis (95% CI: 0.53-0.77, P < 0.001) were noted to be significant. From the analysis, CEA was observed as having better treatment results in terms of stroke events and stroke or death incidences when compared to stenting. Carotid stenting was observed as having lower cases of myocardial infarctions when compared to endarterectomy.
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spelling pubmed-100245982023-03-19 Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis Vasavada, Advait M Singh, Priyansha Firdaus, Arshia Meenashi Sundaram, Dakshin Patel, Malvik Singh, Ganeev Palanisamy, Logesh Ansari, Sana Afreen Thummala, Sumaina Pandya, Harsh Cureus Cardiology Carotid endarterectomy (CEA) is a surgical procedure that treats the narrowed carotid arteries, which may be narrowed by atherosclerosis. Stenting is the insertion of a wire mesh scaffold into the narrowed portion of the carotid artery to keep it open by preventing blood from clotting. Using the study done over 10 years back as a point of reference, this study will seek an update on an assessment comparing CEA and stenting in studies carried out between 2015 and to date. The PICOS (population, intervention, control, outcome, and study designs) criteria were used to construct a set of inclusion and exclusion guidelines. This meta-analysis and systematic review used two forms of investigative analysis; both quantitative and qualitative assessments. From the studies, stroke (95% CI: 0.51-0.71, P < 0.001), myocardial infarction (95% CI: 1.49-3.42, P = 0.001), and stroke or death analysis (95% CI: 0.53-0.77, P < 0.001) were noted to be significant. From the analysis, CEA was observed as having better treatment results in terms of stroke events and stroke or death incidences when compared to stenting. Carotid stenting was observed as having lower cases of myocardial infarctions when compared to endarterectomy. Cureus 2023-02-16 /pmc/articles/PMC10024598/ /pubmed/36942176 http://dx.doi.org/10.7759/cureus.35070 Text en Copyright © 2023, Vasavada et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Vasavada, Advait M
Singh, Priyansha
Firdaus, Arshia
Meenashi Sundaram, Dakshin
Patel, Malvik
Singh, Ganeev
Palanisamy, Logesh
Ansari, Sana Afreen
Thummala, Sumaina
Pandya, Harsh
Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis
title Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis
title_full Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis
title_fullStr Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis
title_full_unstemmed Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis
title_short Carotid Endarterectomy Versus Stenting for the Treatment of Patients With Carotid Artery Stenosis: An Updated Systematic Review and Meta-Analysis
title_sort carotid endarterectomy versus stenting for the treatment of patients with carotid artery stenosis: an updated systematic review and meta-analysis
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024598/
https://www.ncbi.nlm.nih.gov/pubmed/36942176
http://dx.doi.org/10.7759/cureus.35070
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