FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2

FBXW7 is a member of the F-box protein family, which functions as the substrate recognition component of the SCF E3 ubiquitin ligase. FBXW7 is a main tumor suppressor due to its ability to control proteasome-mediated degradation of several oncoproteins such as c-Jun, c-Myc, Cyclin E1, mTOR, and Notc...

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Detalles Bibliográficos
Autores principales: Jiménez-Izquierdo, Rafael, Morrugares, Rosario, Suanes-Cobos, Lucía, Correa-Sáez, Alejandro, Garrido-Rodríguez, Martín, Cerero-Tejero, Laura, Khan, Omar M., de la Luna, Susana, Sancho, Rocío, Calzado, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024693/
https://www.ncbi.nlm.nih.gov/pubmed/36934104
http://dx.doi.org/10.1038/s41419-023-05724-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024693/
https://www.ncbi.nlm.nih.gov/pubmed/36934104
http://dx.doi.org/10.1038/s41419-023-05724-0

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