A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes

Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (CM) constitute a mixed population of ventricular-, atrial-, nodal-like cells, limiting the reliability for studying chamber-specific disease mechanisms. Previous studies characterised CM phenotype based on action potential (AP) morp...

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Detalles Bibliográficos
Autores principales: Altomare, Claudia, Bartolucci, Chiara, Sala, Luca, Balbi, Carolina, Burrello, Jacopo, Pietrogiovanna, Nicole, Burrello, Alessio, Bolis, Sara, Panella, Stefano, Arici, Martina, Krause, Rolf, Rocchetti, Marcella, Severi, Stefano, Barile, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024709/
https://www.ncbi.nlm.nih.gov/pubmed/36934210
http://dx.doi.org/10.1038/s42003-023-04674-9

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