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Probing the Interactions of Lamotrigine and Phenobarbital with Tau Protein: Experimental and Molecular Modeling Studies

Tau, as a small protein in neurons, plays a main role in stabilizing and assembling the internal microtubules. Here, the effects of antiepileptic drugs, including lamotrigine (LTG) and phenobarbital (PHB), on tau protein structure have been investigated by surface plasmon resonance (SPR), fluorescen...

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Detalles Bibliográficos
Autores principales: Gholami, Amirreza, Dehghan, Gholamreza, Rashtbari, Samaneh, Jouyban, Abolghasem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024808/
https://www.ncbi.nlm.nih.gov/pubmed/36945338
http://dx.doi.org/10.5812/ijpr-129599

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