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Matrix stiffness induces epithelial-to-mesenchymal transition via Piezo1-regulated calcium flux in prostate cancer cells

Cells utilize calcium channels as one of the main signaling mechanisms to sense changes in the extracellular space and convert these changes to intracellular signals. Calcium regulates several key signaling networks, such as the induction of EMT. The current study expands on the understanding of how...

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Detalles Bibliográficos
Autores principales: Lopez-Cavestany, Maria, Hahn, Su Bin, Hope, Jacob M., Reckhorn, Noah T., Greenlee, Joshua D., Schwager, Samantha C., VanderBurgh, Jacob A., Reinhart-King, Cynthia A., King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025097/
https://www.ncbi.nlm.nih.gov/pubmed/36950111
http://dx.doi.org/10.1016/j.isci.2023.106275