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Radiotherapy and olaparib in combination for carcinoma of the oesophagus: A phase I study

BACKGROUND AND PURPOSE: Radical concurrent chemoradiotherapy (CRT) for oesophageal cancer is associated with significant morbidity and is unsuitable for some patients. Olaparib, an inhibitor of the DNA repair enzyme poly-(ADP)-ribose polymerase (PARP) has radiosensitising properties and may be bette...

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Detalles Bibliográficos
Autores principales:	Sheikh, Hamid, Ryder, David, Bateman, Andrew, Chalmers, Anthony, Jackson, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025123/ https://www.ncbi.nlm.nih.gov/pubmed/36949958 http://dx.doi.org/10.1016/j.ctro.2023.100614

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