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Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation
Aging is accompanied by chronic low-grade inflammation, but the mechanisms that allow this to persist are not well understood. Ketone bodies are alternative fuels produced when glucose is limited and improve indicators of healthspan in aging mouse models. Moreover, the most abundant ketone body, β-h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025153/ https://www.ncbi.nlm.nih.gov/pubmed/36775129 http://dx.doi.org/10.1016/j.jbc.2023.103005 |