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chi sequences switch the RecBCD helicase–nuclease complex from degradative to replicative modes during the completion of DNA replication

Accurately completing DNA replication when two forks converge is essential to genomic stability. The RecBCD helicase–nuclease complex plays a central role in completion by promoting resection and joining of the excess DNA created when replisomes converge. chi sequences alter RecBCD activity and loca...

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Detalles Bibliográficos
Autores principales: Hamilton, Nicklas A., Jehru, Avery E., Samples, William N., Wendel, Brian M., Mokhtari, Parisa D., Courcelle, Charmain T., Courcelle, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025158/
https://www.ncbi.nlm.nih.gov/pubmed/36781123
http://dx.doi.org/10.1016/j.jbc.2023.103013