Cargando…

Tumor P70S6K hyperactivation is inversely associated with tumor-infiltrating lymphocytes in triple-negative breast cancer

PURPOSE: Triple-negative breast cancer (TNBC) is characterized by large heterogeneity and relative lack of available targeted therapies. To find therapeutic strategies for distinct patients with TNBC, several approaches have been used for TNBC clustering, including recently immune and phosphoproteom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jimeno, Rebeca, Mouron, Silvana, Salgado, Roberto, Loi, Sherene, Pérez-Mies, Belén, Sánchez-Bayona, Rodrigo, Manso, Luis, Martínez, Mario, Garrido-García, Ana, Serrano-Pardo, Rosario, Colomer, Ramón, Quintela-Fandino, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Brief Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025236/ https://www.ncbi.nlm.nih.gov/pubmed/36508123 http://dx.doi.org/10.1007/s12094-022-03006-3

Ejemplares similares

Personalising and targeting antiangiogenic resistance: a complex and multifactorial approach
por: Bueno, Maria J, et al.
Publicado: (2017)

FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1
por: Mouron, Silvana, et al.
Publicado: (2021)

Usefulness and real-world outcomes of next generation sequencing testing in patients with cancer: an observational study on the impact of selection based on clinical judgement
por: Colomer, Ramon, et al.
Publicado: (2023)

Monitoring vascular normalization: new opportunities for mitochondrial inhibitors in breast cancer
por: Mouron, Silvana, et al.
Publicado: (2021)

Nintedanib plus letrozole in early breast cancer: a phase 0/I pharmacodynamic, pharmacokinetic, and safety clinical trial of combined FGFR1 and aromatase inhibition
por: Quintela-Fandino, Miguel, et al.
Publicado: (2019)

Analysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal Resistance
por: Manso, Luis, et al.
Publicado: (2016)

[6]-Gingerol-Derived Semi-Synthetic Compound SSi6 Inhibits Tumor Growth and Metastatic Dissemination in Triple-Negative Breast Cancer Xenograft Models
por: Luna-Dulcey, Liany, et al.
Publicado: (2021)

p27(Kip1) V109G as a biomarker for CDK4/6 inhibitors indication in hormone receptor–positive breast cancer
por: Mouron, Silvana, et al.
Publicado: (2023)

Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy
por: Loi, Sherene
Publicado: (2013)

Emerging role of Fatty acid synthase in tumor initiation: implications for cancer prevention
por: Bueno, Maria J., et al.
Publicado: (2020)

When should we order a next generation sequencing test in a patient with cancer?
por: Colomer, Ramon, et al.
Publicado: (2020)

Clinical Validity and Utility of Tumor-Infiltrating Lymphocytes in Routine Clinical Practice for Breast Cancer Patients: Current and Future Directions
por: Wein, Lironne, et al.
Publicado: (2017)

Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment
por: Yang, Min, et al.
Publicado: (2020)

Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells
por: Hühn, Daniela, et al.
Publicado: (2021)

Monitoring vascular normalization induced by antiangiogenic treatment with 18F‐fluoromisonidazole‐PET
por: Hernández-Agudo, Elena, et al.
Publicado: (2015)

Determination of Mammalian Target of Rapamycin Hyperactivation as Prognostic Factor in Well-Differentiated Neuroendocrine Tumors
por: Lamberti, G., et al.
Publicado: (2017)

Residual disease and immune infiltration as a new surrogate endpoint for TNBC post neoadjuvant chemotherapy
por: Luen, Stephen L., et al.
Publicado: (2019)

Immuno-priming durvalumab with bevacizumab in HER2-negative advanced breast cancer: a pilot clinical trial
por: Quintela-Fandino, Miguel, et al.
Publicado: (2020)

Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
por: Ricke, Robin M., et al.
Publicado: (2011)

Hyperactivated endolysosomal trafficking in melanoma
por: Alonso-Curbelo, Direna, et al.
Publicado: (2015)

Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling
por: Choi, Junghwa, et al.
Publicado: (2020)

Relevance of tumor-infiltrating lymphocytes in breast cancer
por: Dushyanthen, Sathana, et al.
Publicado: (2015)

The mechanics of hyperactivation in adhered human sperm
por: Ooi, E. H, et al.
Publicado: (2014)

Flagellar hyperactivation of bull and boar spermatozoa
por: Harayama, Hiroshi
Publicado: (2018)

Enhancement of rat spermatozoal hyperactivation by progesterone
por: MIYAZAWA, Yuki, et al.
Publicado: (2023)

Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A
por: Mouron, S., et al.
Publicado: (2022)

Tissue-Dependent Tumor Microenvironments and Their Impact on Immunotherapy Responses
por: Oliver, Amanda J., et al.
Publicado: (2018)

Checkpoint blockade in the treatment of breast cancer: current status and future directions
por: Wein, Lironne, et al.
Publicado: (2018)

RUNX1/EGFR pathway contributes to STAT3 activation and tumor growth caused by hyperactivated mTORC1
por: Lin, Wei, et al.
Publicado: (2021)

Serotonergic signals enhanced hamster sperm hyperactivation
por: SAKAMOTO, Chiyori, et al.
Publicado: (2021)

Signalling by senescent melanocytes hyperactivates hair growth
por: Wang, Xiaojie, et al.
Publicado: (2023)

Bi-steric mTORC1 inhibitors induce apoptotic cell death in tumor models with hyperactivated mTORC1
por: Du, Heng, et al.
Publicado: (2023)

Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes
por: Rodriguez-Acebes, Sara, et al.
Publicado: (2018)

In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer
por: Zagorac, Ivana, et al.
Publicado: (2018)

Critically short telomeres and toxicity of chemotherapy in early breast cancer
por: Quintela-Fandino, Miguel, et al.
Publicado: (2017)

Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data
por: Lönnstedt, Ingrid M, et al.
Publicado: (2014)

Estrogen suppresses melatonin-enhanced hyperactivation of hamster spermatozoa
por: FUJINOKI, Masakatsu, et al.
Publicado: (2015)

Platelets and COVID-19: Inflammation, Hyperactivation and Additional Questions
por: Koupenova, Milka, et al.
Publicado: (2020)

Protein kinases regulate hyperactivated motility of human sperm
por: Wang, Ya-Yan, et al.
Publicado: (2021)

Eugenol-hyperactivated nymphs of Triatoma infestans become intoxicated faster than non-hyperactivated nymphs when exposed to a permethrin-treated surface
por: Reynoso, Mercedes María Noel, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_62gi0giadu7hj12lul2uroi0fc