Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate

Ferumoxytol (FMX) is an FDA-approved magnetite (Fe(3)O(4)) nanoparticle used to treat iron deficiency anemia that can also be used as an MR imaging agent in patients that can't receive gadolinium. Pharmacological ascorbate (P-AscH-; IV delivery; plasma levels ≈ 20 mM) has shown promise as an ad...

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Detalles Bibliográficos
Autores principales: Petronek, M.S., Teferi, N., Caster, J.M., Stolwijk, J.M., Zaher, A., Buatti, J.M., Hasan, D., Wafa, E.I., Salem, A.K., Gillan, E.G., St – Aubin, J.J., Buettner, G.R., Spitz, D.R., Magnotta, V.A., Allen, B.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025281/
https://www.ncbi.nlm.nih.gov/pubmed/36924683
http://dx.doi.org/10.1016/j.redox.2023.102651

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