Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis-regulatory elements

Cell type-specific transcriptional differences between brain tissues from donors with Alzheimer’s disease (AD) and unaffected controls have been well documented, but few studies have rigorously interrogated the regulatory mechanisms responsible for these alterations. We performed single nucleus mult...

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Detalles Bibliográficos
Autores principales: Anderson, Ashlyn G., Rogers, Brianne B., Loupe, Jacob M., Rodriguez-Nunez, Ivan, Roberts, Sydney C., White, Lauren M., Brazell, J. Nicholas, Bunney, William E., Bunney, Blynn G., Watson, Stanley J., Cochran, J. Nicholas, Myers, Richard M., Rizzardi, Lindsay F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025452/
https://www.ncbi.nlm.nih.gov/pubmed/36950385
http://dx.doi.org/10.1016/j.xgen.2023.100263

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