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Multigenerational mistimed feeding drives circadian reprogramming with an impaired unfolded protein response
Mistimed food intake in relation to the day/night cycle disrupts the synchrony of circadian rhythms in peripheral tissues and increases the risk of metabolic diseases. However, the health effects over generations have seldom been explored. Here, we established a 10-generation mouse model that was co...
Autores principales: | Huang, Kai, Zhang, Tao, Zhang, Wenjun, Gu, Yue, Yu, Pan, Sun, Lanqing, Liu, Zhiwei, Wang, Tao, Xu, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025471/ https://www.ncbi.nlm.nih.gov/pubmed/36950678 http://dx.doi.org/10.3389/fendo.2023.1157165 |
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