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Effects of glycogen synthase kinase-3β activity inhibition on cognitive, behavioral, and hippocampal ultrastructural deficits in adulthood associated with adolescent methamphetamine exposure

OBJECTIVE: Glycogen synthase kinase-3β (GSK3β) has been implicated in the maintenance of synaptic plasticity, memory process, and psychostimulant-induced behavioral effects. Hyperactive GSK3β in the Cornu Ammonis 1 (CA1) subregion of the dorsal hippocampus (DHP) was associated with adolescent metham...

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Detalles Bibliográficos
Autores principales: Yan, Peng, Liu, Jincen, Ma, Haotian, Feng, Yue, Cui, Jingjing, Bai, Yuying, Huang, Xin, Zhu, Yongsheng, Wei, Shuguang, Lai, Jianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025487/
https://www.ncbi.nlm.nih.gov/pubmed/36949769
http://dx.doi.org/10.3389/fnmol.2023.1129553

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