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SOPHIE: Generative Neural Networks Separate Common and Specific Transcriptional Responses

Genome-wide transcriptome profiling identifies genes that are prone to differential expression (DE) across contexts, as well as genes with changes specific to the experimental manipulation. Distinguishing genes that are specifically changed in a context of interest from common differentially express...

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Detalles Bibliográficos
Autores principales: Lee, Alexandra J., Mould, Dallas L., Crawford, Jake, Hu, Dongbo, Powers, Rani K., Doing, Georgia, Costello, James C., Hogan, Deborah A., Greene, Casey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025681/
https://www.ncbi.nlm.nih.gov/pubmed/36216026
http://dx.doi.org/10.1016/j.gpb.2022.09.011