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Considering developmental neurotoxicity in vitro data for human health risk assessment using physiologically-based kinetic modeling: deltamethrin case study
Developmental neurotoxicity (DNT) is a potential hazard of chemicals. Recently, an in vitro testing battery (DNT IVB) was established to complement existing rodent in vivo approaches. Deltamethrin (DLT), a pyrethroid with a well-characterized neurotoxic mode of action, has been selected as a referen...
Autores principales: | Maass, Christian, Schaller, Stephan, Dallmann, André, Bothe, Kathrin, Müller, Dennis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025876/ https://www.ncbi.nlm.nih.gov/pubmed/36637193 http://dx.doi.org/10.1093/toxsci/kfad007 |
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