Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans

HFPO-DA (ammonium, 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate) is a short-chain polyfluorinated alkyl substance (PFAS) used in the manufacture of some types of fluorinated polymers. Like many PFAS, toxicity studies with HFPO-DA indicate the liver is the primary target of toxicity in rodent...

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Detalles Bibliográficos
Autores principales: Heintz, Melissa M, Haws, Laurie C, Klaunig, James E, Cullen, John M, Thompson, Chad M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
In-Depth Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025879/
https://www.ncbi.nlm.nih.gov/pubmed/36629480
http://dx.doi.org/10.1093/toxsci/kfad004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025879/
https://www.ncbi.nlm.nih.gov/pubmed/36629480
http://dx.doi.org/10.1093/toxsci/kfad004

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