Obligate role for Rock1 and Rock2 in adult stem cell viability and function

The ability of stem cells to rapidly proliferate and differentiate is integral to the steady-state maintenance of tissues with high turnover such as the blood and intestine. Mutations that alter these processes can cause primary immunodeficiencies, malignancies and defects in barrier function. The R...

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Detalles Bibliográficos
Autores principales: Sambandam, Arivazhagan, Storm, Elaine, Tauc, Helen, Hackney, Jason A., Garfield, David, Caplazi, Patrick, Liu, John, Zhang, Juan, Zhang, Hua, Duggan, Jeff, Jeet, Surinder, Gierke, Sarah, Chang, Patrick, Wu, Xiumin, Newman, Robert, Tam, Lucinda, Alcantar, Tuija, Wang, Lifen, Roose-Girma, Meron, Modrusan, Zora, Lee, Wyne P., Jasper, Heinrich, de Sauvage, Frederic, Pappu, Rajita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025895/
https://www.ncbi.nlm.nih.gov/pubmed/36950615
http://dx.doi.org/10.1016/j.heliyon.2023.e14238

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