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A straightforward microfluidic-based approach toward optimizing transduction efficiency of HIV-1-derived lentiviral vectors in BCP-ALL cells

BACKGROUND: HIV-1-derived lentiviral vectors (LVs) are capable of transducing human cells by integrating the transgene into the host genome. In order to do that, LVs should have enough time and space to interact with the surface of the target cells. Herein, we used a microfluidic system to facilitat...

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Detalles Bibliográficos
Autores principales: Ahmadi, Seyed Esmaeil, Shabestari, Rima Manafi, kojabad, Amir Asri, Safa, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025989/
https://www.ncbi.nlm.nih.gov/pubmed/36950261
http://dx.doi.org/10.1016/j.btre.2023.e00792