LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells

Chemoresistance and plasticity of tumor-initiating stem-like cells (TICs) promote tumor recurrence and metastasis. The gut-originating endotoxin-TLR4-NANOG oncogenic axis is responsible for the genesis of TICs. This study investigated mechanisms as to how TICs arise through transcriptional, epigenet...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez, Juan Carlos, Chen, Chia-Lin, Machida, Tatsuya, Uthaya Kumar, Dinesh Babu, Tahara, Stanley M., Montana, Jared, Sher, Linda, Liang, Jake, Jung, Jae U., Tsukamoto, Hidekazu, Machida, Keigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025994/
https://www.ncbi.nlm.nih.gov/pubmed/36949755
http://dx.doi.org/10.1016/j.isci.2023.106254

Ejemplares similares

Ejemplares similares