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ARIA in patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease
INTRODUCTION: Lecanemab is a humanized immunoglobulin G1 (IgG1) monoclonal antibody that preferentially targets soluble aggregated Aβ species (protofibrils) with activity at amyloid plaques. Amyloid‐related imaging abnormalities (ARIA) profiles appear to differ for various anti‐amyloid antibodies. H...
Autores principales: | Honig, Lawrence S., Barakos, Jerome, Dhadda, Shobha, Kanekiyo, Michio, Reyderman, Larisa, Irizarry, Michael, Kramer, Lynn D., Swanson, Chad J., Sabbagh, Marwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026083/ https://www.ncbi.nlm.nih.gov/pubmed/36949897 http://dx.doi.org/10.1002/trc2.12377 |
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