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Blended Survival Curves: A New Approach to Extrapolation for Time-to-Event Outcomes from Clinical Trials in Health Technology Assessment

BACKGROUND: Survival extrapolation is essential in cost-effectiveness analysis to quantify the lifetime survival benefit associated with a new intervention, due to the restricted duration of randomized controlled trials (RCTs). Current approaches of extrapolation often assume that the treatment effe...

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Detalles Bibliográficos
Autores principales: Che, Zhaojing, Green, Nathan, Baio, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026162/
https://www.ncbi.nlm.nih.gov/pubmed/36314662
http://dx.doi.org/10.1177/0272989X221134545