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Corticosteroids reduce pathologic interferon responses by downregulating STAT1 in patients with high-risk COVID-19

We do not yet understand exactly how corticosteroids attenuate hyperinflammatory responses and alleviate high-risk coronavirus disease 2019 (COVID-19). We aimed to reveal the molecular mechanisms of hyperinflammation in COVID-19 and the anti-inflammatory effects of corticosteroids in patients with h...

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Detalles Bibliográficos
Autores principales: Jeong, Hyun-Woo, Lee, Jeong Seok, Ko, Jae-Hoon, Hong, Seunghee, Oh, Sang Taek, Choi, Seongkyun, Peck, Kyong Ran, Yang, Ji Hun, Chung, Seok, Kim, Sung-Han, Kim, Yeon-Sook, Shin, Eui-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026241/
https://www.ncbi.nlm.nih.gov/pubmed/36941461
http://dx.doi.org/10.1038/s12276-023-00964-8