Cargando…

Genome-wide identification of copy neutral loss of heterozygosity reveals its possible association with spatial positioning of chromosomes

Loss of heterozygosity (LOH) is a genetic alteration that results from the loss of one allele at a heterozygous locus. In particular, copy neutral LOH (CN-LOH) events are generated, for example, by mitotic homologous recombination after monoallelic defection or gene conversion, resulting in novel ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hyeonjeong, Suyama, Mikita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026252/ https://www.ncbi.nlm.nih.gov/pubmed/36349694 http://dx.doi.org/10.1093/hmg/ddac278

Ejemplares similares

Copy-neutral loss of heterozygosity and chromosome gains and losses are frequent in gastrointestinal stromal tumors
por: Lourenço, Nelson, et al.
Publicado: (2014)

Somatic mosaicism for copy-neutral loss of heterozygosity and DNA copy number variations in the human genome
por: Žilina, Olga, et al.
Publicado: (2015)

Genome-wide Profiling of 8-Oxoguanine Reveals Its Association with Spatial Positioning in Nucleus
por: Yoshihara, Minako, et al.
Publicado: (2014)

Comparative genomic analysis of inbred rat strains reveals the existence of ancestral polymorphisms
por: Kim, Hyeonjeong, et al.
Publicado: (2020)

SNP Array Analysis Reveals Novel Genomic Abnormalities Including Copy Neutral Loss of Heterozygosity in Anaplastic Oligodendrogliomas
por: Idbaih, Ahmed, et al.
Publicado: (2012)

Impact of Copy Neutral Loss of Heterozygosity and Total Genome Aberrations on Survival in Myelodysplastic Syndrome
por: Yeung, Cecilia, et al.
Publicado: (2017)

Neuroendocrine Carcinoma of the Kidney and Bladder with Loss of Heterozygosity and Changes in Chromosome 3 Copy Number
por: Okada, Atsushi, et al.
Publicado: (2015)

Identification of copy neutral loss of heterozygosity on chromosomes 1p, 1q, and 6p among nonsyndromic cleft lip and/or without cleft palate with hypodontia
por: Ghazali, Norliana, et al.
Publicado: (2023)

Correction: SNP Array Analysis Reveals Novel Genomic Abnormalities Including Copy Neutral Loss of Heterozygosity in Anaplastic Oligodendrogliomas
por: Idbaih, Ahmed, et al.
Publicado: (2013)

ChromContact: A web tool for analyzing spatial contact of chromosomes from Hi-C data
por: Sato, Tetsuya, et al.
Publicado: (2015)

Dissecting Loss of Heterozygosity (LOH) in Neurofibromatosis Type 1-Associated Neurofibromas: Importance of Copy Neutral LOH
por: Garcia-Linares, Carles, et al.
Publicado: (2011)

Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AML
por: Stirewalt, D L, et al.
Publicado: (2014)

Clonal evidence for the development of neuroblastoma with extensive copy‐neutral loss of heterozygosity arising in a mature teratoma
por: Ono, Rintaro, et al.
Publicado: (2021)

Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma
por: Hu, Nan, et al.
Publicado: (2010)

Copy number of the Adenomatous Polyposis Coli gene is not always neutral in sporadic colorectal cancers with loss of heterozygosity for the gene
por: Zauber, Peter, et al.
Publicado: (2016)

Massive interstitial copy-neutral loss-of-heterozygosity as evidence for cancer being a disease of the DNA-damage response
por: Kumar, Yogesh, et al.
Publicado: (2015)

Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer
por: Ciani, Yari, et al.
Publicado: (2022)

Copy neutral absence of heterozygosity on chromosome 15 distal long arm: A surrogate marker for Prader–Willi/Angelman syndromes?
por: Ortega, Veronica, et al.
Publicado: (2021)

CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells
por: Boutin, J., et al.
Publicado: (2021)

Comparison of the copy-neutral loss of heterozygosity identified from whole-exome sequencing data using three different tools
por: Lee, Gang-Taik, et al.
Publicado: (2022)

Loss of constitutional heterozygosity on chromosomes 5 and 17 in cholangiocarcinoma.
por: Ding, S. F., et al.
Publicado: (1993)

Loss of heterozygosity on chromosomes 1 and 11 in carcinoma of the pancreas.
por: Ding, S. F., et al.
Publicado: (1992)

Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour.
por: Grundy, R. G., et al.
Publicado: (1998)

A Novel Case of Extreme Thrombocytosis in Acute Myeloid Leukemia Associated With Isochromosome 17q and Copy Neutral Loss of Heterozygosity
por: You, Eunkyoung, et al.
Publicado: (2015)

Loss of Heterozygosity and Copy Number Alterations in Flow-Sorted Bulky Cervical Cancer
por: van den Tillaart, Sabrina A. H. M., et al.
Publicado: (2013)

Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours.
por: Gustafson, C. E., et al.
Publicado: (1994)

Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma.
por: Foulkes, W. D., et al.
Publicado: (1993)

TP53 Mutations in Myeloid Malignancies are either Homozygous or Hemizygous due to Copy Number-Neutral Loss of Heterozygosity or Deletion of 17p
por: Jasek, Monika, et al.
Publicado: (2009)

Possible involvement of silent mutations in cancer pathogenesis and evolution
por: Kikutake, Chie, et al.
Publicado: (2023)

Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression
por: Gu, Jun, et al.
Publicado: (2015)

Uniparental isodisomy caused autosomal recessive diseases: NGS‐based analysis allows the concurrent detection of homogenous variants and copy‐neutral loss of heterozygosity
por: Xiao, Bing, et al.
Publicado: (2019)

Genome-wide identification of exon extension/shrinkage events induced by splice-site-creating mutations
por: Qu, Zhuo, et al.
Publicado: (2022)

Loss of heterozygosity on chromosomes 11 and 17 are markers of recurrence in TCC of the bladder
por: Edwards, J, et al.
Publicado: (2001)

Loss of heterozygosity and amplification on chromosome 11q in human ovarian cancer.
por: Foulkes, W. D., et al.
Publicado: (1993)

Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular Carcinoma
por: Zhang, Wandong, et al.
Publicado: (1990)

Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors
por: Zhang, Zhouwei, et al.
Publicado: (2020)

Pervasive occurrence of splice-site-creating mutations and their possible involvement in genetic disorders
por: Sakaguchi, Narumi, et al.
Publicado: (2022)

Pan‐cancer analysis of mutations in open chromatin regions and their possible association with cancer pathogenesis
por: Kikutake, Chie, et al.
Publicado: (2022)

Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors
por: Kryh, Hanna, et al.
Publicado: (2011)

Y(MAP): a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens
por: Abbey, Darren A, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hs8q17a7fdq7edresqlsr7qv28