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Genome-wide identification of copy neutral loss of heterozygosity reveals its possible association with spatial positioning of chromosomes

Loss of heterozygosity (LOH) is a genetic alteration that results from the loss of one allele at a heterozygous locus. In particular, copy neutral LOH (CN-LOH) events are generated, for example, by mitotic homologous recombination after monoallelic defection or gene conversion, resulting in novel ho...

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Detalles Bibliográficos
Autores principales:	Kim, Hyeonjeong, Suyama, Mikita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026252/ https://www.ncbi.nlm.nih.gov/pubmed/36349694 http://dx.doi.org/10.1093/hmg/ddac278

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