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TFIIH mutations can impact on translational fidelity of the ribosome

TFIIH is a complex essential for transcription of protein-coding genes by RNA polymerase II, DNA repair of UV-lesions and transcription of rRNA by RNA polymerase I. Mutations in TFIIH cause the cancer prone DNA-repair disorder xeroderma pigmentosum (XP) and the developmental and premature aging diso...

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Detalles Bibliográficos
Autores principales: Khalid, Fatima, Phan, Tamara, Qiang, Mingyue, Maity, Pallab, Lasser, Theresa, Wiese, Sebastian, Penzo, Marianna, Alupei, Marius, Orioli, Donata, Scharffetter-Kochanek, Karin, Iben, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026254/
https://www.ncbi.nlm.nih.gov/pubmed/36308430
http://dx.doi.org/10.1093/hmg/ddac268

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