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Screening for obstructive sleep apnoea in post‐treatment cancer patients
BACKGROUND AND AIMS: For cancer patients, comorbid obstructive sleep apnea (OSA) poses additional risk to their surgical/anaesthetic outcomes, quality of life, and survival. However, OSA screening is not well‐established in oncology settings. We tested two screening tools (STOP‐Bang questionnaire [S...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026305/ https://www.ncbi.nlm.nih.gov/pubmed/36512174 http://dx.doi.org/10.1002/cnr2.1740 |
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author | Subramanian, Harini Fuchsova, Veronika Elder, Elisabeth Brand, Alison Howle, Julie DeFazio, Anna Mann, Graham J. Amis, Terence Kairaitis, Kristina |
author_facet | Subramanian, Harini Fuchsova, Veronika Elder, Elisabeth Brand, Alison Howle, Julie DeFazio, Anna Mann, Graham J. Amis, Terence Kairaitis, Kristina |
author_sort | Subramanian, Harini |
collection | PubMed |
description | BACKGROUND AND AIMS: For cancer patients, comorbid obstructive sleep apnea (OSA) poses additional risk to their surgical/anaesthetic outcomes, quality of life, and survival. However, OSA screening is not well‐established in oncology settings. We tested two screening tools (STOP‐Bang questionnaire [SBQ] and the at‐home monitoring device, ApneaLink™Air), for predicting polysomnography (PSG) confirmed OSA in post‐treatment cancer patients. METHODS: Breast (n = 56), endometrial (n = 37) and melanoma patients (n = 50) were recruited from follow‐up clinics at Westmead Hospital (Sydney, Australia). All underwent overnight PSG, 137 completed SBQ, and 99 completed ApneaLink™Air. Positive (PPV) and negative (NPV) predictive values for PSG‐determined moderate‐to‐severe OSA and severe OSA, were calculated using an SBQ threshold ≥3 au and ApneaLink™Air apnoea‐hypopnea index thresholds of ≥10, ≥15 and ≥30 events/h. RESULTS: Both SBQ and ApneaLink™Air had high NPVs (92.7% and 85.2%–95.6% respectively) for severe OSA, but NPVs were lower for moderate‐to‐severe OSA (69.1% and 59.1%–75.5%, respectively). PPV for both tools were relatively low (all <73%). Combining both tools did not improve screening performance. CONCLUSIONS: These screening tools may help identify cancer patients without severe OSA, but both are limited in identifying those with moderate‐to‐severe or severe OSA. PSG remains optimal for adequately identifying and managing comorbid OSA in cancer patients. |
format | Online Article Text |
id | pubmed-10026305 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100263052023-03-21 Screening for obstructive sleep apnoea in post‐treatment cancer patients Subramanian, Harini Fuchsova, Veronika Elder, Elisabeth Brand, Alison Howle, Julie DeFazio, Anna Mann, Graham J. Amis, Terence Kairaitis, Kristina Cancer Rep (Hoboken) Original Articles BACKGROUND AND AIMS: For cancer patients, comorbid obstructive sleep apnea (OSA) poses additional risk to their surgical/anaesthetic outcomes, quality of life, and survival. However, OSA screening is not well‐established in oncology settings. We tested two screening tools (STOP‐Bang questionnaire [SBQ] and the at‐home monitoring device, ApneaLink™Air), for predicting polysomnography (PSG) confirmed OSA in post‐treatment cancer patients. METHODS: Breast (n = 56), endometrial (n = 37) and melanoma patients (n = 50) were recruited from follow‐up clinics at Westmead Hospital (Sydney, Australia). All underwent overnight PSG, 137 completed SBQ, and 99 completed ApneaLink™Air. Positive (PPV) and negative (NPV) predictive values for PSG‐determined moderate‐to‐severe OSA and severe OSA, were calculated using an SBQ threshold ≥3 au and ApneaLink™Air apnoea‐hypopnea index thresholds of ≥10, ≥15 and ≥30 events/h. RESULTS: Both SBQ and ApneaLink™Air had high NPVs (92.7% and 85.2%–95.6% respectively) for severe OSA, but NPVs were lower for moderate‐to‐severe OSA (69.1% and 59.1%–75.5%, respectively). PPV for both tools were relatively low (all <73%). Combining both tools did not improve screening performance. CONCLUSIONS: These screening tools may help identify cancer patients without severe OSA, but both are limited in identifying those with moderate‐to‐severe or severe OSA. PSG remains optimal for adequately identifying and managing comorbid OSA in cancer patients. John Wiley and Sons Inc. 2022-12-13 /pmc/articles/PMC10026305/ /pubmed/36512174 http://dx.doi.org/10.1002/cnr2.1740 Text en © 2022 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Subramanian, Harini Fuchsova, Veronika Elder, Elisabeth Brand, Alison Howle, Julie DeFazio, Anna Mann, Graham J. Amis, Terence Kairaitis, Kristina Screening for obstructive sleep apnoea in post‐treatment cancer patients |
title | Screening for obstructive sleep apnoea in post‐treatment cancer patients |
title_full | Screening for obstructive sleep apnoea in post‐treatment cancer patients |
title_fullStr | Screening for obstructive sleep apnoea in post‐treatment cancer patients |
title_full_unstemmed | Screening for obstructive sleep apnoea in post‐treatment cancer patients |
title_short | Screening for obstructive sleep apnoea in post‐treatment cancer patients |
title_sort | screening for obstructive sleep apnoea in post‐treatment cancer patients |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026305/ https://www.ncbi.nlm.nih.gov/pubmed/36512174 http://dx.doi.org/10.1002/cnr2.1740 |
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