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Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants

Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the ex...

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Detalles Bibliográficos
Autores principales: Susanti, Nora, Purba, Jamalum, Gopas Oetama, M. Yosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026331/
https://www.ncbi.nlm.nih.gov/pubmed/36950469
http://dx.doi.org/10.4103/japtr.japtr_539_22
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author Susanti, Nora
Purba, Jamalum
Gopas Oetama, M. Yosia
author_facet Susanti, Nora
Purba, Jamalum
Gopas Oetama, M. Yosia
author_sort Susanti, Nora
collection PubMed
description Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the extract and is impractical so it needs to be redissolved. The method of using surfactants can be used as a suspending agent, a mixture of two types of surfactants gives variations in hydrophilic and lipophilic balance (HLB), by finding the optimum HLB value to create optimum solution stability and organoleptic, various mixture ratios were carried out with test parameters such as organoleptic, pH, viscosity, particle size, and components of chemical compounds. The results show that the optimum HLB of S. benzoin is 12.7 in surfactants Tween 80 and Span 80.
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spelling pubmed-100263312023-03-21 Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants Susanti, Nora Purba, Jamalum Gopas Oetama, M. Yosia J Adv Pharm Technol Res Original Article Styrax benzoin is a type of incense produced in North Tapanuli, Indonesia. The content of metabolite compounds provides wide use in pharmaceuticals. The occurrence of deposits in the extract makes this preparation unstable; this instability creates problems, especially in the concentration of the extract and is impractical so it needs to be redissolved. The method of using surfactants can be used as a suspending agent, a mixture of two types of surfactants gives variations in hydrophilic and lipophilic balance (HLB), by finding the optimum HLB value to create optimum solution stability and organoleptic, various mixture ratios were carried out with test parameters such as organoleptic, pH, viscosity, particle size, and components of chemical compounds. The results show that the optimum HLB of S. benzoin is 12.7 in surfactants Tween 80 and Span 80. Wolters Kluwer - Medknow 2023 2023-01-20 /pmc/articles/PMC10026331/ /pubmed/36950469 http://dx.doi.org/10.4103/japtr.japtr_539_22 Text en Copyright: © 2023 Journal of Advanced Pharmaceutical Technology & Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Susanti, Nora
Purba, Jamalum
Gopas Oetama, M. Yosia
Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants
title Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants
title_full Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants
title_fullStr Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants
title_full_unstemmed Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants
title_short Increasing the stability of incense gum extract (Styrax benzoin) with a mixture of surfactants
title_sort increasing the stability of incense gum extract (styrax benzoin) with a mixture of surfactants
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026331/
https://www.ncbi.nlm.nih.gov/pubmed/36950469
http://dx.doi.org/10.4103/japtr.japtr_539_22
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