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BCL7A is silenced by hypermethylation to promote acute myeloid leukemia

BACKGROUND: Recent massive sequencing studies have revealed that SWI/SNF complexes are among the most frequently altered functional entities in solid tumors. However, the role of SWI/SNF in acute myeloid leukemia is poorly understood. To date, SWI/SNF complexes are thought to be oncogenic in AML or,...

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Detalles Bibliográficos
Autores principales: Patiño-Mercau, Juan Rodrigo, Baliñas-Gavira, Carlos, Andrades, Alvaro, Benitez-Cantos, Maria S., Rot, Ana Ercegovič, Rodriguez, Maria Isabel, Álvarez-Pérez, Juan Carlos, Cuadros, Marta, Medina, Pedro P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026484/
https://www.ncbi.nlm.nih.gov/pubmed/36941700
http://dx.doi.org/10.1186/s40364-023-00472-x