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Probiotic E. coli treatment mediates antimicrobial human β-defensin synthesis and fecal excretion in humans

Inducible epithelial human β-defensins (hBD) play an important role in intestinal barrier function. In vitro studies showed that clinically effective probiotics induce antimicrobial hBD-2. Here, we aimed to assess the in vivo effect in healthy volunteers and also addressed how defensins affect probi...

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Detalles Bibliográficos
Autores principales: Möndel, M, Schroeder, B O, Zimmermann, K, Huber, H, Nuding, S, Beisner, J, Fellermann, K, Stange, E F, Wehkamp, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Society for Mucosal Immunology. Published by Elsevier Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026704/
https://www.ncbi.nlm.nih.gov/pubmed/19129752
http://dx.doi.org/10.1038/mi.2008.77