Cargando…

Probiotic E. coli treatment mediates antimicrobial human β-defensin synthesis and fecal excretion in humans

Inducible epithelial human β-defensins (hBD) play an important role in intestinal barrier function. In vitro studies showed that clinically effective probiotics induce antimicrobial hBD-2. Here, we aimed to assess the in vivo effect in healthy volunteers and also addressed how defensins affect probi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Möndel, M, Schroeder, B O, Zimmermann, K, Huber, H, Nuding, S, Beisner, J, Fellermann, K, Stange, E F, Wehkamp, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	© Society for Mucosal Immunology. Published by Elsevier Inc. 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026704/ https://www.ncbi.nlm.nih.gov/pubmed/19129752 http://dx.doi.org/10.1038/mi.2008.77

Ejemplares similares

Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide
por: Schroeder, B O, et al.
Publicado: (2015)

Innate immunity includes defensins
por: Jäger, Simon, et al.
Publicado: (2012)

Cell-mediated reduction of human β-defensin 1: a major role for mucosal thioredoxin
por: Jaeger, S U, et al.
Publicado: (2013)

Gastric Antimicrobial Peptides Fail to Eradicate Helicobacter pylori Infection Due to Selective Induction and Resistance
por: Nuding, Sabine, et al.
Publicado: (2013)

Human α-Defensin 5(1–9) and Human β-Defensin 2 Improve Metabolic Parameters and Gut Barrier Function in Mice Fed a Western-Style Diet
por: Filipe Rosa, Louisa, et al.
Publicado: (2023)

Fragmentation of Human Neutrophil α-Defensin 4 to Combat Multidrug Resistant Bacteria
por: Ehmann, Dirk, et al.
Publicado: (2020)

Proteolytic Degradation of reduced Human Beta Defensin 1 generates a Novel Antibiotic Octapeptide
por: Wendler, Judith, et al.
Publicado: (2019)

Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
por: Ehmann, D., et al.
Publicado: (2019)

Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis
por: Koeninger, Louis, et al.
Publicado: (2020)

Antimicrobial Peptides in Gastrointestinal Inflammation
por: Jäger, Simon, et al.
Publicado: (2010)

Antimicrobial peptides and gut microbiota in homeostasis and pathology
por: Ostaff, Maureen J, et al.
Publicado: (2013)

Antibacterial activity of human defensins against Staphylococcus aureus and Escherichia coli
por: Bolatchiev, Albert
Publicado: (2020)

A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease
por: Gacesa, R., et al.
Publicado: (2021)

The Antimicrobial Peptides Human β-Defensins Induce the Secretion of Angiogenin in Human Dermal Fibroblasts
por: Umehara, Yoshie, et al.
Publicado: (2022)

Variations in the interaction of human defensins with Escherichia coli: Possible implications in bacterial killing
por: Mathew, Basil, et al.
Publicado: (2017)

Antagonism of Adherent Invasive E. coli LF82 With Human α-defensin 5 in the Follicle-associated Epithelium of Patients With Ileal Crohn’s Disease
por: Alkaissi, Lina Y, et al.
Publicado: (2020)

Antimicrobial Human β-Defensins in the Colon and Their Role in Infectious and Non-Infectious Diseases
por: Cobo, Eduardo R., et al.
Publicado: (2013)

The capsule of Bacillus anthracis protects it from the bactericidal activity of human defensins and other cationic antimicrobial peptides
por: O’Brien, David K., et al.
Publicado: (2022)

Antiviral Mechanisms of Human Defensins
por: Wilson, Sarah S., et al.
Publicado: (2013)

Excretion of Urine Mixed with Air and Fecal Material
por: Lee, Sik, et al.
Publicado: (2011)

Fecal Excretion of Mycobacterium leprae, Burkina Faso
por: Singh, Ajay Vir, et al.
Publicado: (2021)

Fecal Excretion of Mycobacterium leprae, Burkina Faso
por: Millogo, Anselme, et al.
Publicado: (2021)

Antimicrobial Resistance in Fecal Escherichia coli from Humans and Pigs at Farms at Different Levels of Intensification
por: Lunha, Kamonwan, et al.
Publicado: (2020)

Balantioides coli Fecal Excretion in Hunted Wild Cervids (Cervus elaphus and Dama dama) from Portugal
por: Mega, João, et al.
Publicado: (2022)

Children who develop allergy have low fecal alpha-defensin levels but high beta-defensin levels in infancy
por: Savilahti, Emma, et al.
Publicado: (2011)

Enterohemorrhagic Escherichia coli Excretion by Child and Her Cat
por: Busch, Ulrich, et al.
Publicado: (2007)

The First Salamander Defensin Antimicrobial Peptide
por: Meng, Ping, et al.
Publicado: (2013)

Defensins and Other Antimicrobial Peptides and Proteins
por: Lehrer, Robert I., et al.
Publicado: (2005)

Expression of mouse beta defensin 2 in escherichia coli and its broad-spectrum antimicrobial activity
por: Gong, Tianxiang, et al.
Publicado: (2011)

Human β-Defensin 4 with Non-Native Disulfide Bridges Exhibit Antimicrobial Activity
por: Sharma, Himanshu, et al.
Publicado: (2015)

Expression and Functional Characterization of a Novel Antimicrobial Peptide: Human Beta-Defensin 118
por: Lin, Qian, et al.
Publicado: (2020)

Directional and balancing selection in human beta-defensins
por: Hollox, Edward J, et al.
Publicado: (2008)

Flagellin Induces β-Defensin 2 in Human Colonic Ex vivo Infection with Enterohemorrhagic Escherichia coli
por: Lewis, Steven B., et al.
Publicado: (2016)

Increased fecal human beta-defensin-2 expression in preterm infants is associated with allergic disease development in early childhood
por: Hua, Man-Chin, et al.
Publicado: (2022)

Towards the Application of Human Defensins as Antivirals
por: Park, Mee Sook, et al.
Publicado: (2018)

Defensins: defenders of human reproductive health
por: Zhai, Yu-Jia, et al.
Publicado: (2022)

Human Beta Defensin 3 induces maturation of human langerhans cell like dendritic cells: An antimicrobial peptide that functions as an endogenous adjuvant
por: Ferris, Laura K., et al.
Publicado: (2012)

Human Beta Defensins and Cancer: Contradictions and Common Ground
por: Ghosh, Santosh K., et al.
Publicado: (2019)

Prolonged Gut Dysbiosis and Fecal Excretion of Hepatitis A Virus in Patients Infected with Human Immunodeficiency Virus
por: Ishizaka, Aya, et al.
Publicado: (2021)

Evaluation of human β‑defensins in the cerebrospinal fluid of suspected meningitis
por: Jaleel, Lena K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_08a4ktfeeif7ad8vh35g6sgkuu