Cargando…

Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial

In preclinical studies, a new antituberculosis drug regimen markedly reduced the time required to achieve relapse-free cure. This study aimed to preliminarily evaluate the efficacy and safety of this four-month regimen, consisting of clofazimine, prothionamide, pyrazinamide and ethambutol, with a st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Xubin, Gui, Xuwei, Yao, Lan, Ma, Jun, He, Yifan, Lou, Hai, Gu, Jin, Ying, Ruoyan, Chen, Liping, Sun, Qin, Liu, Yidian, Ho, Chih-Ming, Lee, Bai-Yu, Clemens, Daniel L., Horwitz, Marcus A., Ding, Xianting, Hao, Xiaohui, Yang, Hua, Sha, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Tuberculosis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026740/ https://www.ncbi.nlm.nih.gov/pubmed/36872899 http://dx.doi.org/10.1080/22221751.2023.2187247

Ejemplares similares

Designing molecular diagnostics for current tuberculosis drug regimens
por: Georghiou, Sophia B., et al.
Publicado: (2023)

What are the most efficacious treatment regimens for isoniazid-resistant tuberculosis? A systematic review and network meta-analysis
por: Stagg, H R, et al.
Publicado: (2016)

Treatment outcomes of patients with MDR-TB in Nepal on a current programmatic standardised regimen: retrospective single-centre study
por: Ghimire, Samiksha, et al.
Publicado: (2020)

Adjunctive Zoledronate + IL-2 administrations enhance anti-tuberculosis Vγ2Vδ2 T-effector populations, and improve treatment outcome of multidrug-resistant tuberculosis(1)
por: Shen, Hongbo, et al.
Publicado: (2022)

Prompt recognition of infectious pulmonary tuberculosis is critical to achieving elimination goals: a retrospective cohort study
por: Heffernan, Courtney, et al.
Publicado: (2020)

Discrepancy in the transmissibility of multidrug-resistant mycobacterium tuberculosis in urban and rural areas in China
por: Li, Meng, et al.
Publicado: (2023)

Mycobacterium paragordonae is an emerging pathogen in human pulmonary disease: clinical features, antimicrobial susceptibility testing and outcomes
por: Li, Yuanchun, et al.
Publicado: (2022)

High clustering rate and genotypic drug-susceptibility screening for the newly recommended anti-tuberculosis drugs among global extensively drug-resistant Mycobacterium tuberculosis isolates
por: Trisakul, Kanwara, et al.
Publicado: (2022)

Real-world impact of the fixed-dose combination on improving treatment outcomes of drug-susceptible tuberculosis: a comparative study using multiyear national tuberculosis patient data
por: Ki, Min Seo, et al.
Publicado: (2023)

Pictorial essay: Orbital tuberculosis
por: Narula, Mahender K, et al.
Publicado: (2010)

Primary laryngeal tuberculosis mimicking laryngeal carcinoma: CT scan features
por: El Kettani, N Ech-Cherif, et al.
Publicado: (2010)

Imaging features of extraaxial musculoskeletal tuberculosis
por: Vanhoenacker, Filip M, et al.
Publicado: (2009)

Magnetic resonance imaging in central nervous system tuberculosis
por: Trivedi, Richa, et al.
Publicado: (2009)

Revisiting tuberculous pleurisy: pleural fluid characteristics and diagnostic yield of mycobacterial culture in an endemic area
por: Ruan, Sheng-Yuan, et al.
Publicado: (2012)

Association of diabetes and tuberculosis: impact on treatment and post-treatment outcomes
por: Jiménez-Corona, María Eugenia, et al.
Publicado: (2013)

BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients
por: Ashenafi, Senait, et al.
Publicado: (2013)

Incremental value of T-SPOT.TB for diagnosis of active pulmonary tuberculosis in children in a high-burden setting: a multivariable analysis
por: Ling, Daphne I, et al.
Publicado: (2013)

Use of the Xpert® MTB/RIF assay for diagnosing pulmonary tuberculosis comorbidity and multidrug-resistant TB in obstetrics and gynaecology inpatient wards at the University Teaching Hospital, Lusaka, Zambia
por: Bates, Matthew, et al.
Publicado: (2013)

Achieving high treatment success for multidrug-resistant TB in Africa: initiation and scale-up of MDR TB care in Ethiopia—an observational cohort study
por: Meressa, Daniel, et al.
Publicado: (2015)

Recent TB transmission, clustering and predictors of large clusters in London, 2010–2012: results from first 3 years of universal MIRU-VNTR strain typing
por: Hamblion, Esther L, et al.
Publicado: (2016)

The impact of BCG vaccination on tuberculin skin test responses in children is age dependent: evidence to be considered when screening children for tuberculosis infection
por: Seddon, James A, et al.
Publicado: (2016)

Hypoxia and tissue destruction in pulmonary TB
por: Belton, Moerida, et al.
Publicado: (2016)

Evaluation of prediagnosis emergency department presentations in patients with active tuberculosis: the role of chest radiography, risk factors and symptoms
por: Appleton, S C, et al.
Publicado: (2017)

Alcohol drinking and cigarette smoking in relation to risk of active tuberculosis: prospective cohort study
por: Soh, Avril Zixin, et al.
Publicado: (2017)

Initiation, scale-up and outcomes of the Cambodian National MDR-TB programme 2006–2016: hospital and community-based treatment through an NGO–NTP partnership
por: Sam, Sophan, et al.
Publicado: (2018)

Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity
por: Paris, Luisa, et al.
Publicado: (2017)

High prevalence of latent tuberculosis and bloodborne virus infection in a homeless population
por: Aldridge, Robert W, et al.
Publicado: (2018)

Targeting protein biotinylation enhances tuberculosis chemotherapy
por: Tiwari, Divya, et al.
Publicado: (2018)

Incidence of tuberculosis and the influence of surveillance strategy on tuberculosis case-finding and all-cause mortality: a cluster randomised trial in Indian neonates vaccinated with BCG
por: Jenum, Synne, et al.
Publicado: (2018)

Monitoring tuberculosis contact tracing outcomes in Western Sydney, Australia
por: Parvaresh, Laila, et al.
Publicado: (2018)

Post-tuberculous fibrosing mediastinitis: a review of the literature
por: Wu, Zhe, et al.
Publicado: (2017)

An evaluation of tuberculosis contact investigations against national standards
por: Cavany, Sean M, et al.
Publicado: (2017)

The impact of HIV and antiretroviral therapy on TB risk in children: a systematic review and meta-analysis
por: Dodd, P J, et al.
Publicado: (2017)

Identification of eight-protein biosignature for diagnosis of tuberculosis
por: Yang, Qianting, et al.
Publicado: (2020)

Association between bacterial homoplastic variants and radiological pathology in tuberculosis
por: Grandjean, Louis, et al.
Publicado: (2020)

Presentation and healthcare delays among people with tuberculosis in London, and the impact on treatment outcome
por: Evenden, Poppy, et al.
Publicado: (2019)

Extensive global movement of multidrug-resistant M. tuberculosis strains revealed by whole-genome analysis
por: Cohen, Keira A, et al.
Publicado: (2019)

Biomarkers of iron metabolism facilitate clinical diagnosis in M ycobacterium tuberculosis infection
por: Dai, Youchao, et al.
Publicado: (2019)

Delivery of long-term-injectable agents for TB by lay carers: pragmatic randomised trial
por: Cohen, Danielle B, et al.
Publicado: (2020)

Human pathogenic Mycobacterium kansasii (former subtype I) with zoonotic potential isolated from a diseased indoor pet cat, Japan
por: Fukano, Hanako, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rkgvrf423asrns4t7sirgp7uup