IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury

Cerebral small vessel disease and brain white matter injury are worsened by cardiovascular risk factors including obesity. Molecular pathways in cerebral endothelial cells activated by chronic cerebrovascular risk factors alter cell-cell signaling, blocking endogenous and post-ischemic white matter...

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Detalles Bibliográficos
Autores principales: Xiao, Guanxi, Kumar, Rosie, Komuro, Yutaro, Burguet, Jasmine, Kakarla, Visesha, Azizkhanian, Ida, Sheth, Sunil A., Williams, Christopher K., Zhang, Xinhai R., Macknicki, Michal, Brumm, Andrew, Kawaguchi, Riki, Mai, Phu, Kaneko, Naoki, Vinters, Harry V., Carmichael, S. Thomas, Havton, Leif A., DeCarli, Charles, Hinman, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026849/
https://www.ncbi.nlm.nih.gov/pubmed/36543124
http://dx.doi.org/10.1016/j.celrep.2022.111848

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