Pruning and thresholding approach for methylation risk scores in multi-ancestry populations

Recent efforts have focused on developing methylation risk scores (MRS), a weighted sum of the individual’s DNA methylation (DNAm) values of pre-selected CpG sites. Most of the current MRS approaches that utilize Epigenome-wide association studies (EWAS) summary statistics only include genome-wide s...

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Detalles Bibliográficos
Autores principales: Chen, Junyu, Gatev, Evan, Everson, Todd, Conneely, Karen N., Koen, Nastassja, Epstein, Michael P., Kobor, Michael S., Zar, Heather J., Stein, Dan J., Hüls, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026878/
https://www.ncbi.nlm.nih.gov/pubmed/36908043
http://dx.doi.org/10.1080/15592294.2023.2187172

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