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Attacking the public health crisis of hepatocellular carcinoma at its roots
As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026951/ https://www.ncbi.nlm.nih.gov/pubmed/35989555 http://dx.doi.org/10.1002/hep.32741 |
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author | Lee, Hannah M. Lidofsky, Steven D. Taddei, Tamar H. Townshend‐Bulson, Lisa J. |
author_facet | Lee, Hannah M. Lidofsky, Steven D. Taddei, Tamar H. Townshend‐Bulson, Lisa J. |
author_sort | Lee, Hannah M. |
collection | PubMed |
description | As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease. Despite this, progress in identifying at‐risk individuals and early detection of HCC in these populations have lagged behind treatment advances.The lack of consensus may undermine widespread adoption of surveillance programs, thus preventing HCC detection at a curable stage. This public policy corner piece focuses on opportunities for prevention of HCC by focusing on its principal risk factors: viral hepatitis, NAFLD, and alcohol‐related liver disease, and three key action points to reverse the course of this public health crisis: 1) Awareness and education; 2) Screening and diagnosis, and 3) Partnerships and advocacy. |
format | Online Article Text |
id | pubmed-10026951 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-100269512023-03-21 Attacking the public health crisis of hepatocellular carcinoma at its roots Lee, Hannah M. Lidofsky, Steven D. Taddei, Tamar H. Townshend‐Bulson, Lisa J. Hepatology Public Policy Corner As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease. Despite this, progress in identifying at‐risk individuals and early detection of HCC in these populations have lagged behind treatment advances.The lack of consensus may undermine widespread adoption of surveillance programs, thus preventing HCC detection at a curable stage. This public policy corner piece focuses on opportunities for prevention of HCC by focusing on its principal risk factors: viral hepatitis, NAFLD, and alcohol‐related liver disease, and three key action points to reverse the course of this public health crisis: 1) Awareness and education; 2) Screening and diagnosis, and 3) Partnerships and advocacy. Lippincott Williams & Wilkins 2023-04 2022-10-11 /pmc/articles/PMC10026951/ /pubmed/35989555 http://dx.doi.org/10.1002/hep.32741 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Public Policy Corner Lee, Hannah M. Lidofsky, Steven D. Taddei, Tamar H. Townshend‐Bulson, Lisa J. Attacking the public health crisis of hepatocellular carcinoma at its roots |
title | Attacking the public health crisis of hepatocellular carcinoma at its roots |
title_full | Attacking the public health crisis of hepatocellular carcinoma at its roots |
title_fullStr | Attacking the public health crisis of hepatocellular carcinoma at its roots |
title_full_unstemmed | Attacking the public health crisis of hepatocellular carcinoma at its roots |
title_short | Attacking the public health crisis of hepatocellular carcinoma at its roots |
title_sort | attacking the public health crisis of hepatocellular carcinoma at its roots |
topic | Public Policy Corner |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026951/ https://www.ncbi.nlm.nih.gov/pubmed/35989555 http://dx.doi.org/10.1002/hep.32741 |
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