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Attacking the public health crisis of hepatocellular carcinoma at its roots

As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alc...

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Autores principales: Lee, Hannah M., Lidofsky, Steven D., Taddei, Tamar H., Townshend‐Bulson, Lisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026951/
https://www.ncbi.nlm.nih.gov/pubmed/35989555
http://dx.doi.org/10.1002/hep.32741
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author Lee, Hannah M.
Lidofsky, Steven D.
Taddei, Tamar H.
Townshend‐Bulson, Lisa J.
author_facet Lee, Hannah M.
Lidofsky, Steven D.
Taddei, Tamar H.
Townshend‐Bulson, Lisa J.
author_sort Lee, Hannah M.
collection PubMed
description As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease. Despite this, progress in identifying at‐risk individuals and early detection of HCC in these populations have lagged behind treatment advances.The lack of consensus may undermine widespread adoption of surveillance programs, thus preventing HCC detection at a curable stage. This public policy corner piece focuses on opportunities for prevention of HCC by focusing on its principal risk factors: viral hepatitis, NAFLD, and alcohol‐related liver disease, and three key action points to reverse the course of this public health crisis: 1) Awareness and education; 2) Screening and diagnosis, and 3) Partnerships and advocacy.
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spelling pubmed-100269512023-03-21 Attacking the public health crisis of hepatocellular carcinoma at its roots Lee, Hannah M. Lidofsky, Steven D. Taddei, Tamar H. Townshend‐Bulson, Lisa J. Hepatology Public Policy Corner As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease. Despite this, progress in identifying at‐risk individuals and early detection of HCC in these populations have lagged behind treatment advances.The lack of consensus may undermine widespread adoption of surveillance programs, thus preventing HCC detection at a curable stage. This public policy corner piece focuses on opportunities for prevention of HCC by focusing on its principal risk factors: viral hepatitis, NAFLD, and alcohol‐related liver disease, and three key action points to reverse the course of this public health crisis: 1) Awareness and education; 2) Screening and diagnosis, and 3) Partnerships and advocacy. Lippincott Williams & Wilkins 2023-04 2022-10-11 /pmc/articles/PMC10026951/ /pubmed/35989555 http://dx.doi.org/10.1002/hep.32741 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Public Policy Corner
Lee, Hannah M.
Lidofsky, Steven D.
Taddei, Tamar H.
Townshend‐Bulson, Lisa J.
Attacking the public health crisis of hepatocellular carcinoma at its roots
title Attacking the public health crisis of hepatocellular carcinoma at its roots
title_full Attacking the public health crisis of hepatocellular carcinoma at its roots
title_fullStr Attacking the public health crisis of hepatocellular carcinoma at its roots
title_full_unstemmed Attacking the public health crisis of hepatocellular carcinoma at its roots
title_short Attacking the public health crisis of hepatocellular carcinoma at its roots
title_sort attacking the public health crisis of hepatocellular carcinoma at its roots
topic Public Policy Corner
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026951/
https://www.ncbi.nlm.nih.gov/pubmed/35989555
http://dx.doi.org/10.1002/hep.32741
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