Macrophage Galactose Lectin Contributes to the Regulation of FVIII (Factor VIII) Clearance in Mice—Brief Report

Although most plasma FVIII (Factor VIII) circulates in complex with VWF (von Willebrand factor), a minority (3%–5%) circulates as free-FVIII, which is rapidly cleared. Consequently, 20% of total FVIII may be cleared as free-FVIII. Critically, the mechanisms of free-FVIII clearance remain poorly unde...

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Detalles Bibliográficos
Autores principales: Ward, Soracha E., Guest, Thomas, Byrne, Ciara, Lopes, Patricia, O’Sullivan, Jamie M., Doherty, Dearbhla, O’Connell, David, Gutierrez Llaneza, Sara, Chion, Alain, Fazavana, Judicael, Fallon, Padraic G., Preston, Roger J.S., Johnsen, Jill M., Pipe, Steven W., Turecek, Peter L., O’Donnell, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026961/
https://www.ncbi.nlm.nih.gov/pubmed/36727518
http://dx.doi.org/10.1161/ATVBAHA.122.317807

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