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11β-HSD1 determines the extent of muscle atrophy in a model of acute exacerbation of COPD

Muscle atrophy is an extrapulmonary complication of acute exacerbations (AE) in chronic obstructive pulmonary disease (COPD). The endogenous production and therapeutic application of glucocorticoids (GCs) have been implicated as drivers of muscle loss in AE-COPD. The enzyme 11 β-hydroxysteroid dehyd...

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Detalles Bibliográficos
Autores principales:	Webster, Justine M., Waaijenberg, Kelsy, van de Worp, Wouter R. P. H., Kelders, Marco C. J. M., Lambrichts, Sara, Martin, Claire, Verhaegen, Frank, Van der Heyden, Brent, Smith, Charlotte, Lavery, Gareth G., Schols, Annemie M. W. J., Hardy, Rowan S., Langen, Ramon C. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027082/ https://www.ncbi.nlm.nih.gov/pubmed/36807882 http://dx.doi.org/10.1152/ajplung.00009.2022

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