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Electrochemical preparation and the characterizations of poly(3,5-diamino 1,2,4-triazole) film for the selective determination of pyridoxine in pharmaceutical formulations

This work describes the synthesis and characterization of a polymeric film of 3,5-diamino 1,2,4-triazole on a pencil graphite electrode for the selective sensing of pyridoxine (PY). The PGE was modified using the electropolymerization process by the potentiodynamic method. The polymerized electrode...

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Detalles Bibliográficos
Autores principales: Antherjanam, Santhy, Saraswathyamma, Beena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Versita 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027263/
https://www.ncbi.nlm.nih.gov/pubmed/37362795
http://dx.doi.org/10.1007/s11696-023-02777-5
Descripción
Sumario:This work describes the synthesis and characterization of a polymeric film of 3,5-diamino 1,2,4-triazole on a pencil graphite electrode for the selective sensing of pyridoxine (PY). The PGE was modified using the electropolymerization process by the potentiodynamic method. The polymerized electrode (PDAT/PGE) was characterized by IR, SEM, AFM, cyclic voltammetry, and electrochemical impedance spectroscopy. PY undergoes irreversible oxidation at 0.79 V on PDAT/PGE in phosphate buffer of pH 5. Using the differential pulse voltammetric technique (DPV), PY showed a linear range from 5 to 950 μM with a lower detection limit of 2.96 μM. The PDAT/PGE was applied for the analytical determination of PY in pharmaceutical tablets with good recovery. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11696-023-02777-5.