Cargando…
Ion permeation pathway within the internal pore of P2X receptor channels
P2X receptor channels are trimeric ATP-activated ion channels expressed in neuronal and non-neuronal cells that are attractive therapeutic targets for human disorders. Seven subtypes of P2X receptor channels have been identified in mammals that can form both homomeric and heteromeric channels. P2X1–...
Autores principales: | Tam, Stephanie W, Huffer, Kate, Li, Mufeng, Swartz, Kenton J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027316/ https://www.ncbi.nlm.nih.gov/pubmed/36940138 http://dx.doi.org/10.7554/eLife.84796 |
Ejemplares similares
-
The ion selectivity filter is not an activation gate in TRPV1-3 channels
por: Jara-Oseguera, Andrés, et al.
Publicado: (2019) -
Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP
por: Li, Mufeng, et al.
Publicado: (2019) -
Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms
por: Huffer, Katherine E, et al.
Publicado: (2020) -
Molecular determinants of permeation in a fluoride-specific ion channel
por: Last, Nicholas B, et al.
Publicado: (2017) -
Unmasking coupling between channel gating and ion permeation in the muscle nicotinic receptor
por: Strikwerda, John R, et al.
Publicado: (2021)