A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super‐enhancers in maintaining EBV latency

We probed the lifecycle of Epstein‐Barr virus (EBV) on a cell‐by‐cell basis using single cell RNA sequencing (scRNA‐seq) data from nine publicly available lymphoblastoid cell lines (LCLs). While the majority of LCLs comprised cells containing EBV in the latent phase, two other clusters of cells were...

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Detalles Bibliográficos
Autores principales: Yan, Bingyu, Wang, Chong, Chakravorty, Srishti, Zhang, Zonghao, Kadadi, Simran D., Zhuang, Yuxin, Sirit, Isabella, Hu, Yonghua, Jung, Minwoo, Sahoo, Subhransu S., Wang, Luopin, Shao, Kunming, Anderson, Nicole L., Trujillo‐Ochoa, Jorge L., Briggs, Scott D., Liu, Xing, Olson, Matthew R., Afzali, Behdad, Zhao, Bo, Kazemian, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027397/
https://www.ncbi.nlm.nih.gov/pubmed/36453088
http://dx.doi.org/10.1002/jmv.28362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027397/
https://www.ncbi.nlm.nih.gov/pubmed/36453088
http://dx.doi.org/10.1002/jmv.28362

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