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A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super‐enhancers in maintaining EBV latency
We probed the lifecycle of Epstein‐Barr virus (EBV) on a cell‐by‐cell basis using single cell RNA sequencing (scRNA‐seq) data from nine publicly available lymphoblastoid cell lines (LCLs). While the majority of LCLs comprised cells containing EBV in the latent phase, two other clusters of cells were...
Autores principales: | Yan, Bingyu, Wang, Chong, Chakravorty, Srishti, Zhang, Zonghao, Kadadi, Simran D., Zhuang, Yuxin, Sirit, Isabella, Hu, Yonghua, Jung, Minwoo, Sahoo, Subhransu S., Wang, Luopin, Shao, Kunming, Anderson, Nicole L., Trujillo‐Ochoa, Jorge L., Briggs, Scott D., Liu, Xing, Olson, Matthew R., Afzali, Behdad, Zhao, Bo, Kazemian, Majid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027397/ https://www.ncbi.nlm.nih.gov/pubmed/36453088 http://dx.doi.org/10.1002/jmv.28362 |
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