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Pharmacokinetic profiling of quinazoline-4(3H)-one analogs as EGFR inhibitors: 3D-QSAR modeling, molecular docking studies and the design of therapeutic agents

OBJECTIVES: Breast tumor is ranked as the most common tumor type identified among women globally with over 1.7 million cases annually, representing 11.9% of the total number of cancer cases. Approved anti-breast tumor drugs exhibit several side effects and some patients develop resistance during the...

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Detalles Bibliográficos
Autores principales: Abdullahi, Sagiru Hamza, Uzairu, Adamu, Shallangwa, Gideon Adamu, Uba, Sani, Umar, Abdullahi Bello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027554/
https://www.ncbi.nlm.nih.gov/pubmed/36959916
http://dx.doi.org/10.1016/j.jtumed.2023.02.015